{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Li Z"],"pubmed_abstract":["<h4>Background</h4><i>Akkermansia muciniphila</i> is a member of the gut microbiome, using mucin as sources of carbon, nitrogen, and energy. Since the first discovery of this unique bacterium in 2004, <i>A. muciniphila</i> has been extensively studied. It is considered a promising \"next-generation beneficial microbe.\" The purpose of this paper is to sort out the research status and summarize the hotspots through bibliometric analysis of the publications of <i>A. muciniphila.</i><h4>Methods</h4>The publications about <i>A. muciniphila</i> from January 2004 to February 2022 were obtained from the Web of Science Core Collection. Visualization analyses were performed using three bibliometric tools and GraphPad Prism.<h4>Results</h4>A total of 1,478 published documents were analyzed. Annual publication number grew from 1 in 2004 to 336 in 2021, with China being the leading producer (33.36%). De Vos, Willem M was the most productive author with the highest H-index (documents = 56, H-index = 37), followed by Cani, Patrice D (documents = 35, H-index = 25). And Scientific Reports published the most papers. <i>PNAS</i> was the keystone taxa in this field, with high betweenness centrality (0.11) and high frequency. The keywords with high frequency in recent years include: oxidative stress, diet, metformin, fecal microbiota transplantation, short-chain fatty acids, polyphenols, microbiota metabolites and so on. The keyword \"oxidative stress\" was observed to be increasing in frequency recently.<h4>Conclusion</h4>Over time, the scope of the research on the clinical uses of <i>A. muciniphila</i> has gradually increased, and was gradually deepened and developed toward a more precise level. <i>A. muciniphila</i> is likely to remain a research hotspot in the foreseeable future and may contribute to human health."],"journal":["Frontiers in microbiology"],"pagination":["1037708"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9685322"],"repository":["biostudies-literature"],"pubmed_title":["Global trends in <i>Akkermansia muciniphila</i> research: A bibliometric visualization."],"pmcid":["PMC9685322"],"pubmed_authors":["Liu X","Ke H","Lin Q","Li Z","Wang P","Chen Y","Wang Y","Chen S"],"additional_accession":[]},"is_claimable":false,"name":"Global trends in <i>Akkermansia muciniphila</i> research: A bibliometric visualization.","description":"<h4>Background</h4><i>Akkermansia muciniphila</i> is a member of the gut microbiome, using mucin as sources of carbon, nitrogen, and energy. Since the first discovery of this unique bacterium in 2004, <i>A. muciniphila</i> has been extensively studied. It is considered a promising \"next-generation beneficial microbe.\" The purpose of this paper is to sort out the research status and summarize the hotspots through bibliometric analysis of the publications of <i>A. muciniphila.</i><h4>Methods</h4>The publications about <i>A. muciniphila</i> from January 2004 to February 2022 were obtained from the Web of Science Core Collection. Visualization analyses were performed using three bibliometric tools and GraphPad Prism.<h4>Results</h4>A total of 1,478 published documents were analyzed. Annual publication number grew from 1 in 2004 to 336 in 2021, with China being the leading producer (33.36%). De Vos, Willem M was the most productive author with the highest H-index (documents = 56, H-index = 37), followed by Cani, Patrice D (documents = 35, H-index = 25). And Scientific Reports published the most papers. <i>PNAS</i> was the keystone taxa in this field, with high betweenness centrality (0.11) and high frequency. The keywords with high frequency in recent years include: oxidative stress, diet, metformin, fecal microbiota transplantation, short-chain fatty acids, polyphenols, microbiota metabolites and so on. The keyword \"oxidative stress\" was observed to be increasing in frequency recently.<h4>Conclusion</h4>Over time, the scope of the research on the clinical uses of <i>A. muciniphila</i> has gradually increased, and was gradually deepened and developed toward a more precise level. <i>A. muciniphila</i> is likely to remain a research hotspot in the foreseeable future and may contribute to human health.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-04T19:47:46.35Z","creation":"2025-02-19T03:00:05.671Z"},"accession":"S-EPMC9685322","cross_references":{"pubmed":["36439840"],"doi":["10.3389/fmicb.2022.1037708"]}}