biostudies-literatureUnknown13Li Z<h4>Background</h4><i>Akkermansia muciniphila</i> is a member of the gut microbiome, using mucin as sources of carbon, nitrogen, and energy. Since the first discovery of this unique bacterium in 2004, <i>A. muciniphila</i> has been extensively studied. It is considered a promising "next-generation beneficial microbe." The purpose of this paper is to sort out the research status and summarize the hotspots through bibliometric analysis of the publications of <i>A. muciniphila.</i><h4>Methods</h4>The publications about <i>A. muciniphila</i> from January 2004 to February 2022 were obtained from the Web of Science Core Collection. Visualization analyses were performed using three bibliometric tools and GraphPad Prism.<h4>Results</h4>A total of 1,478 published documents were analyzed. Annual publication number grew from 1 in 2004 to 336 in 2021, with China being the leading producer (33.36%). De Vos, Willem M was the most productive author with the highest H-index (documents = 56, H-index = 37), followed by Cani, Patrice D (documents = 35, H-index = 25). And Scientific Reports published the most papers. <i>PNAS</i> was the keystone taxa in this field, with high betweenness centrality (0.11) and high frequency. The keywords with high frequency in recent years include: oxidative stress, diet, metformin, fecal microbiota transplantation, short-chain fatty acids, polyphenols, microbiota metabolites and so on. The keyword "oxidative stress" was observed to be increasing in frequency recently.<h4>Conclusion</h4>Over time, the scope of the research on the clinical uses of <i>A. muciniphila</i> has gradually increased, and was gradually deepened and developed toward a more precise level. <i>A. muciniphila</i> is likely to remain a research hotspot in the foreseeable future and may contribute to human health.Frontiers in microbiology1037708https://www.ebi.ac.uk/biostudies/studies/S-EPMC9685322biostudies-literatureGlobal trends in <i>Akkermansia muciniphila</i> research: A bibliometric visualization.PMC9685322Liu XKe HLin QLi ZWang PChen YWang YChen SfalseGlobal trends in <i>Akkermansia muciniphila</i> research: A bibliometric visualization.<h4>Background</h4><i>Akkermansia muciniphila</i> is a member of the gut microbiome, using mucin as sources of carbon, nitrogen, and energy. Since the first discovery of this unique bacterium in 2004, <i>A. muciniphila</i> has been extensively studied. It is considered a promising "next-generation beneficial microbe." The purpose of this paper is to sort out the research status and summarize the hotspots through bibliometric analysis of the publications of <i>A. muciniphila.</i><h4>Methods</h4>The publications about <i>A. muciniphila</i> from January 2004 to February 2022 were obtained from the Web of Science Core Collection. Visualization analyses were performed using three bibliometric tools and GraphPad Prism.<h4>Results</h4>A total of 1,478 published documents were analyzed. Annual publication number grew from 1 in 2004 to 336 in 2021, with China being the leading producer (33.36%). De Vos, Willem M was the most productive author with the highest H-index (documents = 56, H-index = 37), followed by Cani, Patrice D (documents = 35, H-index = 25). And Scientific Reports published the most papers. <i>PNAS</i> was the keystone taxa in this field, with high betweenness centrality (0.11) and high frequency. The keywords with high frequency in recent years include: oxidative stress, diet, metformin, fecal microbiota transplantation, short-chain fatty acids, polyphenols, microbiota metabolites and so on. The keyword "oxidative stress" was observed to be increasing in frequency recently.<h4>Conclusion</h4>Over time, the scope of the research on the clinical uses of <i>A. muciniphila</i> has gradually increased, and was gradually deepened and developed toward a more precise level. <i>A. muciniphila</i> is likely to remain a research hotspot in the foreseeable future and may contribute to human health.2022-01-01T00:00:00Z20222025-04-04T19:47:46.35Z2025-02-19T03:00:05.671ZS-EPMC96853223643984010.3389/fmicb.2022.1037708