biostudies-literatureSchild AKDeutsche ForschungsgemeinschaftUniversitätsklinikum Köln1215-1223https://www.ebi.ac.uk/biostudies/studies/S-EPMC9686246biostudies-literatureUnknown270(3)<h4>Background</h4>A fraction of patients with asymptomatic to mild/moderate acute COVID-19 disease report cognitive deficits as part of the post-COVID-19 syndrome. This study aimed to assess the neuropsychological profile of these patients.<h4>Methods</h4>Assessment at baseline (three months or more following acute COVID-19) of a monocentric prospective cohort of patients with post-COVID-19 syndrome. Multidomain neuropsychological tests were performed, and questionnaires on depression, anxiety, fatigue, sleep, and general health status were administered.<h4>Results</h4>Of the 58 patients screened, six were excluded due to possible alternative causes of cognitive impairment (major depression, neurodegenerative disease). Of the remaining 52 individuals, only one had a below-threshold screenJournal of neurologyMultidomain cognitive impairment in non-hospitalized patients with the post-COVID-19 syndrome: results from a prospective monocentric cohort.PMC9686246PR 1274/8-1Scharfenberg DLulling JZeyen PSturmer SJessen FKessler JFranke CWarnke CKlein KFink GROnur OASchweitzer FSahin DMaier FGoereci YSchild AKMeiberth DfalseMultidomain cognitive impairment in non-hospitalized patients with the post-COVID-19 syndrome: results from a prospective monocentric cohort.<h4>Background</h4>A fraction of patients with asymptomatic to mild/moderate acute COVID-19 disease report cognitive deficits as part of the post-COVID-19 syndrome. This study aimed to assess the neuropsychological profile of these patients.<h4>Methods</h4>Assessment at baseline (three months or more following acute COVID-19) of a monocentric prospective cohort of patients with post-COVID-19 syndrome. Multidomain neuropsychological tests were performed, and questionnaires on depression, anxiety, fatigue, sleep, and general health status were administered.<h4>Results</h4>Of the 58 patients screened, six were excluded due to possible alternative causes of cognitive impairment (major depression, neurodegenerative disease). Of the remaining 52 individuals, only one had a below-threshold screen2023-01-01T00:00:00Z2023 Mar2025-04-04T08:44:42.492Z2025-04-04T08:44:42.492ZS-EPMC96862463642266910.1007/s00415-022-11444-w