{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(11)"],"submitter":["Priante E"],"pubmed_abstract":["<h4>Background</h4>Premature newborns represent a vulnerable population, at high risk of acquiring nosocomial infections during neonatal intensive care unit (NICU) admission. Multidrug-resistant organisms represent the greatest concern due to their intrinsic virulence and the limited therapeutic options. Resistant <i>Enterobacterales</i> are a growing threat for critically ill neonates, with increasing numbers of NICU outbreaks caused by extended-spectrum beta-lactamase (ESBL)-producing <i>Enterobacterales</i> being described. This study reports the early detection and successful control of an outbreak caused by ESBL-producing <i>Klebsiella pneumoniae</i> (ESBL-KP) in an Italian NICU in February 2021.<h4>Results</h4>A total of 13 newborns tested positive for ESBL-KP between 2-9 February 20"],"journal":["Antibiotics (Basel, Switzerland)"],"pagination":["1649"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9686647"],"repository":["biostudies-literature"],"pubmed_title":["Successful Control of an Outbreak by Phenotypically Identified Extended-Spectrum Beta-Lactamase-Producing <i>Klebsiella pneumoniae</i> in a Neonatal Intensive Care Unit."],"pmcid":["PMC9686647"],"pubmed_authors":["Stano P","Dal Bello F","Lolli E","Boschetto M","Priante E","Dona D","Baldo V","Baraldi E","Contessa C","Minotti C","De Canale E"],"additional_accession":[]},"is_claimable":false,"name":"Successful Control of an Outbreak by Phenotypically Identified Extended-Spectrum Beta-Lactamase-Producing <i>Klebsiella pneumoniae</i> in a Neonatal Intensive Care Unit.","description":"<h4>Background</h4>Premature newborns represent a vulnerable population, at high risk of acquiring nosocomial infections during neonatal intensive care unit (NICU) admission. Multidrug-resistant organisms represent the greatest concern due to their intrinsic virulence and the limited therapeutic options. Resistant <i>Enterobacterales</i> are a growing threat for critically ill neonates, with increasing numbers of NICU outbreaks caused by extended-spectrum beta-lactamase (ESBL)-producing <i>Enterobacterales</i> being described. This study reports the early detection and successful control of an outbreak caused by ESBL-producing <i>Klebsiella pneumoniae</i> (ESBL-KP) in an Italian NICU in February 2021.<h4>Results</h4>A total of 13 newborns tested positive for ESBL-KP between 2-9 February 20","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-25T21:03:40.716Z","creation":"2025-04-06T08:34:45.548Z"},"accession":"S-EPMC9686647","cross_references":{"pubmed":["36421293"],"doi":["10.3390/antibiotics11111649"]}}