biostudies-literatureLee BRNational Research Foundation of South KoreaNational Research Foundation of Korea2283https://www.ebi.ac.uk/biostudies/studies/S-EPMC9687642biostudies-literatureUnknown11(11)In plants, prolonged drought induces oxidative stress, leading to a loss of reducing potential in redox components. Abscisic acid (ABA) is a representative hormonal signal regulating stress responses. This study aimed to investigate the physiological significance of dimethylthiourea (DMTU, an H₂O₂ scavenger) in the hormonal regulation of the antioxidant system and redox control in rapeseed (<i>Brassica napus</i> L.) leaves under drought stress. Drought treatment for 10 days provoked oxidative stress, as evidenced by the increase in O₂^•- and H₂O₂ concentrations, and lipid peroxidation levels, and a decrease in leaf water potential. Drought-induced oxidative responses were significantly alleviated by DMTU treatment. The accumuAntioxidants (Basel, Switzerland)Dimethylthiourea Alleviates Drought Stress by Suppressing Hydrogen Peroxide-Dependent Abscisic Acid-Mediated Oxidative Responses in an Antagonistic Interaction with Salicylic Acid in <i>Brassica napus</i> Leaves.PMC9687642NRF-2021R1A4A1031220Kim THLa VHMamun MABae DWLee BRPark SHfalseDimethylthiourea Alleviates Drought Stress by Suppressing Hydrogen Peroxide-Dependent Abscisic Acid-Mediated Oxidative Responses in an Antagonistic Interaction with Salicylic Acid in <i>Brassica napus</i> Leaves.In plants, prolonged drought induces oxidative stress, leading to a loss of reducing potential in redox components. Abscisic acid (ABA) is a representative hormonal signal regulating stress responses. This study aimed to investigate the physiological significance of dimethylthiourea (DMTU, an H₂O₂ scavenger) in the hormonal regulation of the antioxidant system and redox control in rapeseed (<i>Brassica napus</i> L.) leaves under drought stress. Drought treatment for 10 days provoked oxidative stress, as evidenced by the increase in O₂^•- and H₂O₂ concentrations, and lipid peroxidation levels, and a decrease in leaf water potential. Drought-induced oxidative responses were significantly alleviated by DMTU treatment. The accumu2022-01-01T00:00:00Z2022 Nov2025-04-05T10:57:40.21Z2025-04-05T10:57:40.21ZS-EPMC96876423642146810.3390/antiox11112283