{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Tu Z"],"funding":["Natural Science Foundation of Anhui Province","National Natural Science Foundation of China"],"pagination":["942"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9687718"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(11)"],"pubmed_abstract":["Point-of-care testing methods for the rapid and sensitive screening of pathogenic bacteria are urgently needed because of the high number of outbreaks of microbial infections and foodborne diseases. In this study, we developed a highly sensitive and multiplex lateral flow assay (LFA) for the simultaneous detection of <i>Pseudomonas aeruginosa</i> and <i>Salmonella typhimurium</i> in complex samples by using wheat germ agglutinin (WGA)-modified magnetic quantum dots (Mag@QDs) as a universal detection nanoprobe. The Mag@QDs-WGA tag with a 200 nm Fe<sub>3</sub>O<sub>4</sub> core and multiple QD-formed shell was introduced into the LFA biosensor for the universal capture of the two target bacteria and provided the dual amplification effect of fluorescence enhancement and magnetic enrichment fo"],"journal":["Biosensors"],"pubmed_title":["Ultrasensitive Fluorescence Lateral Flow Assay for Simultaneous Detection of <i>Pseudomonas aeruginosa</i> and <i>Salmonella typhimurium</i> via Wheat Germ Agglutinin-Functionalized Magnetic Quantum Dot Nanoprobe."],"pmcid":["PMC9687718"],"funding_grant_id":["81830101","2208085MB29","32200076","81830101, 32200076"],"pubmed_authors":["Yang X","Dong H","Wang C","Wang S","Yu Q","Zheng S","Tu Z","Cheng X","Rong Z"],"additional_accession":[]},"is_claimable":false,"name":"Ultrasensitive Fluorescence Lateral Flow Assay for Simultaneous Detection of <i>Pseudomonas aeruginosa</i> and <i>Salmonella typhimurium</i> via Wheat Germ Agglutinin-Functionalized Magnetic Quantum Dot Nanoprobe.","description":"Point-of-care testing methods for the rapid and sensitive screening of pathogenic bacteria are urgently needed because of the high number of outbreaks of microbial infections and foodborne diseases. In this study, we developed a highly sensitive and multiplex lateral flow assay (LFA) for the simultaneous detection of <i>Pseudomonas aeruginosa</i> and <i>Salmonella typhimurium</i> in complex samples by using wheat germ agglutinin (WGA)-modified magnetic quantum dots (Mag@QDs) as a universal detection nanoprobe. The Mag@QDs-WGA tag with a 200 nm Fe<sub>3</sub>O<sub>4</sub> core and multiple QD-formed shell was introduced into the LFA biosensor for the universal capture of the two target bacteria and provided the dual amplification effect of fluorescence enhancement and magnetic enrichment fo","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-25T21:05:18.651Z","creation":"2025-04-06T08:34:16.688Z"},"accession":"S-EPMC9687718","cross_references":{"pubmed":["36354451"],"doi":["10.3390/bios12110942"]}}