{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Xie KX"],"funding":["Key Laboratory of Spectrochemical Analysis and Instrumentation (Xiamen University), Ministry of Education","National Natural Science Foundation of China","Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi"],"pagination":["1014"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9688416"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(11)"],"pubmed_abstract":["Surface plasmon-coupled emission (SPCE), a novel signal enhancement technology generated by the interactions between surface plasmons and excited fluorophores in close vicinity to metallic film, has shown excellent performance in bioimaging. Variable-angle nanoplasmonic fluorescence microscopy (VANFM), based on an SPCE imaging system, can selectively modulate the imaging depth by controlling the excitation angles. In order to further improve the imaging performance, Au-Ag alloy nanoshuttles were introduced into an Au substrate to mediate the plasmonic properties. Benefiting from the strong localized plasmon effect of the modified SPCE chip, better imaging brightness, signal-to-background ratio and axial resolution for imaging of the cell membrane region were obtained, which fully displays "],"journal":["Biosensors"],"pubmed_title":["Au-Ag Alloy Nanoshuttle Mediated Surface Plasmon Coupling for Enhanced Fluorescence Imaging."],"pmcid":["PMC9688416"],"funding_grant_id":["SCAI2003","2021L402","21874110, 2274137, 21804098, 21974117"],"pubmed_authors":["Li Z","Li YQ","Xie KX","Cao SH","Fang JH"],"additional_accession":[]},"is_claimable":false,"name":"Au-Ag Alloy Nanoshuttle Mediated Surface Plasmon Coupling for Enhanced Fluorescence Imaging.","description":"Surface plasmon-coupled emission (SPCE), a novel signal enhancement technology generated by the interactions between surface plasmons and excited fluorophores in close vicinity to metallic film, has shown excellent performance in bioimaging. Variable-angle nanoplasmonic fluorescence microscopy (VANFM), based on an SPCE imaging system, can selectively modulate the imaging depth by controlling the excitation angles. In order to further improve the imaging performance, Au-Ag alloy nanoshuttles were introduced into an Au substrate to mediate the plasmonic properties. Benefiting from the strong localized plasmon effect of the modified SPCE chip, better imaging brightness, signal-to-background ratio and axial resolution for imaging of the cell membrane region were obtained, which fully displays ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-18T15:00:02.938Z","creation":"2025-04-07T01:25:50.399Z"},"accession":"S-EPMC9688416","cross_references":{"pubmed":["36421131"],"doi":["10.3390/bios12111014"]}}