{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kim AL"],"funding":["the Ministry of SMEs and Startups","the Rural Development Administration (RDA)","the National Research Foundation (NRF)","the Ministry of Trade, Industry and Energy"],"pagination":["3088"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9697443"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(22)"],"pubmed_abstract":["<i>Cannabis</i> (<i>Cannabis sativa</i> L.) is widely cultivated and studied for its psychoactive and medicinal properties. As the major cannabinoids are present in acidic forms in <i>Cannabis</i> plants, non-enzymatic processes, such as decarboxylation, are crucial for their conversion to neutral active cannabinoid forms. Herein, we detected the levels of cannabidivarin (CBDV), cannabidiol (CBD), cannabichromene (CBC), and Δ9-tetrahydrocannabinol (Δ9-THC) in the leaves and vegetative shoots of five commercial <i>Cannabis</i> cultivars using a combination of relatively simple extraction, decarboxylation, and high-performance liquid chromatography analyses. The CBDV, CBC, and Δ9-THC levels were 6.3-114.9, 34.4-187.2, and 57.6-407.4 μg/g, respectively, and the CBD levels were the highest, ra"],"journal":["Plants (Basel, Switzerland)"],"pubmed_title":["Profiling Cannabinoid Contents and Expression Levels of Corresponding Biosynthetic Genes in Commercial <i>Cannabis</i> (<i>Cannabis sativa</i> L.) Cultivars."],"pmcid":["PMC9697443"],"funding_grant_id":["2020R1I1A1A01072914","PJ01652303","20012892","1425151434"],"pubmed_authors":["Choi HW","Kim AL","Yun YJ","Hong CH","Kim YC","Shim HJ","Lee JH"],"additional_accession":[]},"is_claimable":false,"name":"Profiling Cannabinoid Contents and Expression Levels of Corresponding Biosynthetic Genes in Commercial <i>Cannabis</i> (<i>Cannabis sativa</i> L.) Cultivars.","description":"<i>Cannabis</i> (<i>Cannabis sativa</i> L.) is widely cultivated and studied for its psychoactive and medicinal properties. As the major cannabinoids are present in acidic forms in <i>Cannabis</i> plants, non-enzymatic processes, such as decarboxylation, are crucial for their conversion to neutral active cannabinoid forms. Herein, we detected the levels of cannabidivarin (CBDV), cannabidiol (CBD), cannabichromene (CBC), and Δ9-tetrahydrocannabinol (Δ9-THC) in the leaves and vegetative shoots of five commercial <i>Cannabis</i> cultivars using a combination of relatively simple extraction, decarboxylation, and high-performance liquid chromatography analyses. The CBDV, CBC, and Δ9-THC levels were 6.3-114.9, 34.4-187.2, and 57.6-407.4 μg/g, respectively, and the CBD levels were the highest, ra","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2026-06-21T03:11:27.281Z","creation":"2025-04-06T23:22:31.476Z"},"accession":"S-EPMC9697443","cross_references":{"pubmed":["36432817"],"doi":["10.3390/plants11223088"]}}