{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Alcala-Santiago A"],"funding":["Consejería de Salud de la Junta de Andalucía and co-funded by the European Regional Development Fund(ERDF-FEDER)","Consejería de Salud de la Junta de Andalucía"],"pagination":["14256"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9699081"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["23(22)"],"pubmed_abstract":["Vitamin D (VD) is a fat-soluble vitamin, and pivotal for maintaining health. Several genetic markers have been related to a deficient VD status; these markers could confer an increased risk to develop osteoporosis and other chronic diseases. A VD deficiency could also be a determinant of a severe COVID-19 disease. This study aimed to interrogate genetic/biological databases on the biological implications of a VD deficiency and its association with diseases, to further explore its link with COVID-19. The genetic variants of both a VD deficiency and COVID-19 were identified in the genome-wide association studies (GWAS) catalog and other sources. We conducted enrichment analyses (considering corrected p-values < 0.05 as statistically significant) of the pathways, and gene-disease associations"],"journal":["International journal of molecular sciences"],"pubmed_title":["Vitamin D Deficiency and COVID-19: A Biological Database Study on Pathways and Gene-Disease Associations."],"pmcid":["PMC9699081"],"funding_grant_id":["PECOVID-0200-2020"],"pubmed_authors":["Gil A","Jimenez-Sousa MA","Sanchez MJ","Molina-Montes E","Alcala-Santiago A","Rodriguez-Barranco M","Rava M"],"additional_accession":[]},"is_claimable":false,"name":"Vitamin D Deficiency and COVID-19: A Biological Database Study on Pathways and Gene-Disease Associations.","description":"Vitamin D (VD) is a fat-soluble vitamin, and pivotal for maintaining health. Several genetic markers have been related to a deficient VD status; these markers could confer an increased risk to develop osteoporosis and other chronic diseases. A VD deficiency could also be a determinant of a severe COVID-19 disease. This study aimed to interrogate genetic/biological databases on the biological implications of a VD deficiency and its association with diseases, to further explore its link with COVID-19. The genetic variants of both a VD deficiency and COVID-19 were identified in the genome-wide association studies (GWAS) catalog and other sources. We conducted enrichment analyses (considering corrected p-values < 0.05 as statistically significant) of the pathways, and gene-disease associations","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2026-04-08T15:52:31.011Z","creation":"2024-10-18T09:21:49.358Z"},"accession":"S-EPMC9699081","cross_references":{"pubmed":["36430729"],"doi":["10.3390/ijms232214256"]}}