{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dantas ACS"],"funding":["Improvement of Higher Education Personnel","CAPES-PRINT/UFBA","Coordenação de Aperfeicoamento de Pessoal de Nível Superior","CRP—ICGEB RESEARCH GRANT 2020 Project","International Centre for Genetic Engineering and Biotechnology","Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro"],"pagination":["2424"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9699198"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["14(11)"],"pubmed_abstract":["Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is responsible for causing Coronavirus Disease-2019 (COVID-19), a heterogeneous clinical condition that manifests varying symptom severity according to the demographic profile of the studied population. While many studies have focused on the spread of COVID-19 in large urban centers in Brazil, few have evaluated medium or small cities in the Northeast region. The aims of this study were: (i) to identify risk factors for mortality from SARS-CoV-2 infection, (ii) to evaluate the gene expression patterns of key immune response pathways using nasopharyngeal swabs of COVID-19 patients, and (iii) to identify the circulating SARS-CoV-2 variants in the residents of a medium-sized city in Northeast Brazil. A total of 783 patients infected"],"journal":["Viruses"],"pubmed_title":["Retrospective Analysis of the SARS-CoV-2 Infection Profile in COVID-19 Positive Patients in Vitoria da Conquista, Northeast Brazil."],"pmcid":["PMC9699198"],"funding_grant_id":["CAPES-PRINT/UFBA","CAPES—EDITAL CAPES 11/2020 EPIDEMIAS, PROJETO: 88887.506992/2020-00-AUXPE: 630/2020, Code 001","EDITAL CAPES 11/2020 EPIDEMIAS, PROJETO: 88887.506992/ 2020-00-AUXPE: 510 630/2020","GRANT 2020 Project CRP/BRA20-03, Contract CRP/20/03","E26/202.665/2019 (247400)","Code 001","(E-514 26/202.248/2018(238504); E26/202.665/2019 (247400)","CAPES-PRINT/UFBA (Tema: Inovações em saúde e ambiente como estra-511 tégias para a redução das desigualdades sociais e melhoria da qualidade de vida)","CRP/BRA20-03","E-514 26/202.248/2018 (238504)"],"pubmed_authors":["Giovanetti M","Alcantara LCJ","Moreira PMB","Marques LM","Dantas ACS","Fonseca V","de Oliveira MGG","Nascimento ALP","Oliveira CNT","Santos LA","Gomes CP","Cucco MS","Guimaraes AMS","Infante PDB","Timenetsky J","Oliveira HBM","Pereira TTS","Alves DL","Campos GB","de Medeiros DS","Bittencourt RS","Caitite RJA","Silva LSC","Mistro S","de Oliveira SHP","de Melo FF","Amorim AT","Fritsch HM","Barreto FK","Marinho FAGC"],"additional_accession":[]},"is_claimable":false,"name":"Retrospective Analysis of the SARS-CoV-2 Infection Profile in COVID-19 Positive Patients in Vitoria da Conquista, Northeast Brazil.","description":"Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is responsible for causing Coronavirus Disease-2019 (COVID-19), a heterogeneous clinical condition that manifests varying symptom severity according to the demographic profile of the studied population. While many studies have focused on the spread of COVID-19 in large urban centers in Brazil, few have evaluated medium or small cities in the Northeast region. The aims of this study were: (i) to identify risk factors for mortality from SARS-CoV-2 infection, (ii) to evaluate the gene expression patterns of key immune response pathways using nasopharyngeal swabs of COVID-19 patients, and (iii) to identify the circulating SARS-CoV-2 variants in the residents of a medium-sized city in Northeast Brazil. A total of 783 patients infected","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-19T16:09:47.525Z","creation":"2024-11-08T10:55:13.77Z"},"accession":"S-EPMC9699198","cross_references":{"pubmed":["36366521"],"doi":["10.3390/v14112424"]}}