biostudies-literatureUnknown4(4)Cipriani A<h4>Background</h4>Low QRS voltages (LQRSVs) are a common electrocardiographic feature in patients with light chain amyloidosis (AL) and transthyretin amyloidosis (ATTR) cardiac amyloidosis (CA).<h4>Objectives</h4>The aim of this study was to identify clinical and echocardiographic correlates of LQRSV and to investigate their prognostic significance in patients with CA.<h4>Methods</h4>This was a multicenter, retrospective study performed in 6 CA referral centers including consecutive patients with AL and ATTR CA. LQRSVs were defined as a QRS amplitude ≤5 mm (0.5 mV) in all peripheral leads. The study outcome was cardiovascular (CV) mortality.<h4>Results</h4>Overall, 411 (AL CA: n = 120, ATTR CA: n = 291) patients were included. LQRSVs were present in 66 (55%) patients with AL CA and 103 (3JACC. CardioOncology458-470https://www.ebi.ac.uk/biostudies/studies/S-EPMC9700257biostudies-literatureLow QRS Voltages in Cardiac Amyloidosis: Clinical Correlates and Prognostic Value.PMC9700257Russo DSessarego ERapezzi CAutore CLicchelli LFumagalli CGregori DDi Bella GPerazzolo Marra MZampieri MArgiro ATini GCappelli FDe Michieli LSinagra GPorcari ACanepa MIliceto SSinigiani GDe Gaspari MMusumeci BCipriani AMerlo MLicordari RPerfetto FfalseLow QRS Voltages in Cardiac Amyloidosis: Clinical Correlates and Prognostic Value.<h4>Background</h4>Low QRS voltages (LQRSVs) are a common electrocardiographic feature in patients with light chain amyloidosis (AL) and transthyretin amyloidosis (ATTR) cardiac amyloidosis (CA).<h4>Objectives</h4>The aim of this study was to identify clinical and echocardiographic correlates of LQRSV and to investigate their prognostic significance in patients with CA.<h4>Methods</h4>This was a multicenter, retrospective study performed in 6 CA referral centers including consecutive patients with AL and ATTR CA. LQRSVs were defined as a QRS amplitude ≤5 mm (0.5 mV) in all peripheral leads. The study outcome was cardiovascular (CV) mortality.<h4>Results</h4>Overall, 411 (AL CA: n = 120, ATTR CA: n = 291) patients were included. LQRSVs were present in 66 (55%) patients with AL CA and 103 (32022-01-01T00:00:00Z2022 Nov2025-04-25T20:48:54.842Z2025-04-06T08:34:15.433ZS-EPMC97002573644422510.1016/j.jaccao.2022.08.007