{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ianevski A"],"funding":["NTNU Norwegian University of Science and Technology","Eesti Teadusfondi"],"pagination":["605"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9701656"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["79(12)"],"pubmed_abstract":["The viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development. Here, we briefly reviewed 7 classes of antiviral agents: neutralizing antibodies, neutralizing recombinant soluble human receptors, antiviral CRISPR/Cas systems, interferons, antiviral peptides, antiviral nucleic acid polymers, and antiviral small molecules. Interferons and some small molecules alone or in combinations possess broad-spectrum antiviral activity, which could be beneficial for treatment of emerging and re-emerging viral infections."],"journal":["Cellular and molecular life sciences : CMLS"],"pubmed_title":["Seven classes of antiviral agents."],"pmcid":["PMC9701656"],"funding_grant_id":["MOBTT49"],"pubmed_authors":["Anunnitipat K","Ianevski A","Ahmad S","Oksenych V","Zusinaite E","Bjoras M","Kainov DE","Tenson T"],"additional_accession":[]},"is_claimable":false,"name":"Seven classes of antiviral agents.","description":"The viral epidemics and pandemics have stimulated the development of known and the discovery of novel antiviral agents. About a hundred mono- and combination antiviral drugs have been already approved, whereas thousands are in development. Here, we briefly reviewed 7 classes of antiviral agents: neutralizing antibodies, neutralizing recombinant soluble human receptors, antiviral CRISPR/Cas systems, interferons, antiviral peptides, antiviral nucleic acid polymers, and antiviral small molecules. Interferons and some small molecules alone or in combinations possess broad-spectrum antiviral activity, which could be beneficial for treatment of emerging and re-emerging viral infections.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-04T08:09:02.2Z","creation":"2025-02-19T01:56:22.678Z"},"accession":"S-EPMC9701656","cross_references":{"pubmed":["36436108"],"doi":["10.1007/s00018-022-04635-1"]}}