biostudies-literatureUnknown3Nhan K<h4>Objective</h4>To investigate the effect of acute submaximal exercise, based on the spinal cord injury (SCI) Exercise Guidelines, on cognition and brain-derived neurotrophic factor (BDNF) in people with SCI.<h4>Design</h4>Eight adults (7 males) with traumatic SCI volunteered in this pre-registered pilot study. In randomized order, participants completed submaximal intensity arm cycling (60% of measured peak-power output at 55-60 rpm) for 30 min or time-matched quiet rest (control condition) on separate days. Blood-borne BDNF was measured in serum and plasma at pre-intervention, 0 min and 90 min post-intervention. Cognition was assessed using the Stroop Test and Task-Switching Test on an electronic tablet pre- and 10 min post-intervention.<h4>Results</h4>Submaximal exercise had no effectFrontiers in rehabilitation sciences983345https://www.ebi.ac.uk/biostudies/studies/S-EPMC9701830biostudies-literatureAcute submaximal exercise does not impact aspects of cognition and BDNF in people with spinal cord injury: A pilot study.PMC9701830Little JPNhan KDix GUTodd KRMartin Ginis KAJackson GSWalsh JJVan der Scheer JWfalseAcute submaximal exercise does not impact aspects of cognition and BDNF in people with spinal cord injury: A pilot study.<h4>Objective</h4>To investigate the effect of acute submaximal exercise, based on the spinal cord injury (SCI) Exercise Guidelines, on cognition and brain-derived neurotrophic factor (BDNF) in people with SCI.<h4>Design</h4>Eight adults (7 males) with traumatic SCI volunteered in this pre-registered pilot study. In randomized order, participants completed submaximal intensity arm cycling (60% of measured peak-power output at 55-60 rpm) for 30 min or time-matched quiet rest (control condition) on separate days. Blood-borne BDNF was measured in serum and plasma at pre-intervention, 0 min and 90 min post-intervention. Cognition was assessed using the Stroop Test and Task-Switching Test on an electronic tablet pre- and 10 min post-intervention.<h4>Results</h4>Submaximal exercise had no effect2022-01-01T00:00:00Z20222025-04-21T14:31:54.645Z2025-04-21T14:31:54.645ZS-EPMC97018303645180510.3389/fresc.2022.983345