{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Xue M"],"funding":["Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences","National Key Research and Development Program of China"],"pubmed_abstract":["The influence of dietary probiotic <i>Bacillus amyloliquefaciens</i> on the growth performance, digestive enzyme activity, immune parameters and disease resistance of yellow catfish (<i>Pelteobagrus fulvidraco</i>) was evaluated. Commercial diet (C) or diet containing 10<sup>6</sup> cfu/g <i>B. amyloliquefaciens</i> (T) was fed for 4 weeks, and final weight (FW), specific growth rate (SGR) and feed conversion ratio (FCR) were improved (<i>p<</i>0.05) in the T group. Dietary <i>B. amyloliquefaciens</i> increased protease and amylase activities in the digestive tract after 2 and 4 weeks, respectively. Respiratory burst (RB), plasma lysozyme (LZM) activity, total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) activity were also elevated (<i>p<</i>0.05). Immune-related genes signal transducer and activator of transcription 1 (STATA-1), immunoglobulin M (IgM) and C-type lectin (CTL) were upregulated (<i>p<</i>0.05), but interleukin-1 β (IL-1β) was not (<i>p ></i>0.05). Intestinal microbiota analysis showed that the community structure was significantly different between the two groups; the relative abundance of <i>Cetobacterium</i> was increased but <i>Plesiomonas</i> was decreased in T. Moreover, challenge tests showed that the resistance of fish fed <i>B. amyloliquefaciens</i> against <i>Aeromonas veronii</i> and <i>Edwardsiella ictaluri</i> was significantly enhanced (<i>p<</i>0.05). In conclusion, dietary supplementation of <i>B. amyloliquefaciens</i> can effectively improve the growth performance, digestive enzyme activity, immune responses, intestinal microbiota composition and disease resistance of yellow catfish."],"journal":["Frontiers in cellular and infection microbiology"],"pagination":["1047351"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9702064"],"repository":["biostudies-literature"],"pubmed_title":["Effects of dietary <i>Bacillus amyloliquefaciens</i> on the growth, immune responses, intestinal microbiota composition and disease resistance of yellow catfish, <i>Pelteobagrus fulvidraco</i>."],"pmcid":["PMC9702064"],"pubmed_authors":["Li Y","Fan Y","Hong Y","Xu C","Xue M","Zhou Y","Meng Y","Jiang N","Wu Y","Liu W"],"additional_accession":[]},"is_claimable":false,"name":"Effects of dietary <i>Bacillus amyloliquefaciens</i> on the growth, immune responses, intestinal microbiota composition and disease resistance of yellow catfish, <i>Pelteobagrus fulvidraco</i>.","description":"The influence of dietary probiotic <i>Bacillus amyloliquefaciens</i> on the growth performance, digestive enzyme activity, immune parameters and disease resistance of yellow catfish (<i>Pelteobagrus fulvidraco</i>) was evaluated. Commercial diet (C) or diet containing 10<sup>6</sup> cfu/g <i>B. amyloliquefaciens</i> (T) was fed for 4 weeks, and final weight (FW), specific growth rate (SGR) and feed conversion ratio (FCR) were improved (<i>p<</i>0.05) in the T group. Dietary <i>B. amyloliquefaciens</i> increased protease and amylase activities in the digestive tract after 2 and 4 weeks, respectively. Respiratory burst (RB), plasma lysozyme (LZM) activity, total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) activity were also elevated (<i>p<</i>0.05). Immune-related genes signal transducer and activator of transcription 1 (STATA-1), immunoglobulin M (IgM) and C-type lectin (CTL) were upregulated (<i>p<</i>0.05), but interleukin-1 β (IL-1β) was not (<i>p ></i>0.05). Intestinal microbiota analysis showed that the community structure was significantly different between the two groups; the relative abundance of <i>Cetobacterium</i> was increased but <i>Plesiomonas</i> was decreased in T. Moreover, challenge tests showed that the resistance of fish fed <i>B. amyloliquefaciens</i> against <i>Aeromonas veronii</i> and <i>Edwardsiella ictaluri</i> was significantly enhanced (<i>p<</i>0.05). In conclusion, dietary supplementation of <i>B. amyloliquefaciens</i> can effectively improve the growth performance, digestive enzyme activity, immune responses, intestinal microbiota composition and disease resistance of yellow catfish.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T22:49:33.351Z","creation":"2025-04-19T22:49:33.351Z"},"accession":"S-EPMC9702064","cross_references":{"pubmed":["36452300"],"doi":["10.3389/fcimb.2022.1047351"]}}