{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["13"],"submitter":["Li J"],"pubmed_abstract":["<i>Pelteobagrus vachelli</i> is a freshwater fish with high economic value, but the lack of genome resources has severely restricted its industrial development and population conservation. Here, we constructed the first chromosome-level genome assembly of <i>P. vachelli</i> with a total length of approximately 662.13 Mb and a contig N50 was 14.02 Mb, and scaffolds covering 99.79% of the assembly were anchored to 26 chromosomes. Combining the comparative genome results and transcriptome data under environmental stress (high temperature, hypoxia and <i>Edwardsiella. ictaluri</i> infection), the MAPK signaling pathway, PI3K-Akt signaling pathway and apelin signaling pathway play an important role in environmental adaptation of <i>P. vachelli</i>, and these pathways were interconnected by the ErbB family and involved in cell proliferation, differentiation and apoptosis. Population evolution analysis showed that artificial interventions have affected wild populations of <i>P. vachelli</i>. This study provides a useful genomic information for the genetic breeding of <i>P. vachelli</i>, as well as references for further studies on fish biology and evolution."],"journal":["Frontiers in genetics"],"pagination":["1050192"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9702082"],"repository":["biostudies-literature"],"pubmed_title":["A high-quality chromosome-level genome assembly of <i>Pelteobagrus vachelli</i> provides insights into its environmental adaptation and population history."],"pmcid":["PMC9702082"],"pubmed_authors":["Zhang G","Lai Z","Li J","Zhang K","Yin D","Yin S","Wang T","Ji J","Liu W"],"additional_accession":[]},"is_claimable":false,"name":"A high-quality chromosome-level genome assembly of <i>Pelteobagrus vachelli</i> provides insights into its environmental adaptation and population history.","description":"<i>Pelteobagrus vachelli</i> is a freshwater fish with high economic value, but the lack of genome resources has severely restricted its industrial development and population conservation. Here, we constructed the first chromosome-level genome assembly of <i>P. vachelli</i> with a total length of approximately 662.13 Mb and a contig N50 was 14.02 Mb, and scaffolds covering 99.79% of the assembly were anchored to 26 chromosomes. Combining the comparative genome results and transcriptome data under environmental stress (high temperature, hypoxia and <i>Edwardsiella. ictaluri</i> infection), the MAPK signaling pathway, PI3K-Akt signaling pathway and apelin signaling pathway play an important role in environmental adaptation of <i>P. vachelli</i>, and these pathways were interconnected by the ErbB family and involved in cell proliferation, differentiation and apoptosis. Population evolution analysis showed that artificial interventions have affected wild populations of <i>P. vachelli</i>. This study provides a useful genomic information for the genetic breeding of <i>P. vachelli</i>, as well as references for further studies on fish biology and evolution.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-19T03:33:49.311Z","creation":"2025-04-07T13:42:34.908Z"},"accession":"S-EPMC9702082","cross_references":{"pubmed":["36452160"],"doi":["10.3389/fgene.2022.1050192"]}}