biostudies-literatureUnknown17(11)Verde P<h4>Background</h4> Most SARS-CoV-2 rapid antigen detection tests (RADTs) validation studies have been performed on specimens from COVID-19 patients and negative controls or from mostly symptomatic individuals. Herein we evaluated the diagnostic accuracy of AFIAS COVID-19 Ag, hereinafter denominated as AFIAS, during a COVID-19 screening program surveillance testing conducted among personnel of an Italian military airport. <h4>Methods</h4> Nasopharyngeal swabs (NPSs) were collected from study participants and were analysed by both AFIAS and RT-PCR assay. A questionnaire collecting demographic and exposure data were administered to all participants. AFIAS accuracy parameters including Cohen’s kappa (K) were determined. <h4>Results</h4> Overall, from November 2020 to April 2021, 1294 (NPSs) wPloS onehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9704652biostudies-literatureDiagnostic accuracy of a SARS-CoV-2 rapid antigen test among military and civilian personnel of an Air Force airport in central ItalyPMC9704652Taffon SCostantino ACresta RMarcantonio CSpada EVerde PSimeoni MCampanella CTritarelli EBruni RCiccaglione AMartina ANisini RPisani GfalseDiagnostic accuracy of a SARS-CoV-2 rapid antigen test among military and civilian personnel of an Air Force airport in central Italy<h4>Background</h4> Most SARS-CoV-2 rapid antigen detection tests (RADTs) validation studies have been performed on specimens from COVID-19 patients and negative controls or from mostly symptomatic individuals. Herein we evaluated the diagnostic accuracy of AFIAS COVID-19 Ag, hereinafter denominated as AFIAS, during a COVID-19 screening program surveillance testing conducted among personnel of an Italian military airport. <h4>Methods</h4> Nasopharyngeal swabs (NPSs) were collected from study participants and were analysed by both AFIAS and RT-PCR assay. A questionnaire collecting demographic and exposure data were administered to all participants. AFIAS accuracy parameters including Cohen’s kappa (K) were determined. <h4>Results</h4> Overall, from November 2020 to April 2021, 1294 (NPSs) w2022-01-01T00:00:00Z2022 Jan2025-04-21T16:10:50.047Z2025-02-19T04:37:30.208ZS-EPMC9704652