biostudies-literatureUnknown28(12)Pedersen RMWorldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.Emerging infectious diseases2575-2577https://www.ebi.ac.uk/biostudies/studies/S-EPMC9707601biostudies-literatureOmicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections.PMC9707601Holm DKJohansen ISJensen TGPedersen RMBang LLSydenham TVMadsen LWJustesen USAndersen TETornby DSfalseOmicron BA.5 Neutralization among Vaccine-Boosted Persons with Prior Omicron BA.1/BA.2 Infections.Worldwide, millions of persons have received multiple COVID-19 vaccinations and subsequently recovered from SARS-CoV-2 Omicron breakthrough infections. In 2 small, matched cohorts (n = 12, n = 24) in Denmark, we found Omicron BA.1/BA.2 breakthrough infection after 3-dose BNT162b2 vaccination provided improved Omicron BA.5 neutralization over 3-dose vaccination alone.2022-01-01T00:00:00Z2022 Dec2025-04-22T00:38:52.963Z2025-04-05T19:38:14.875ZS-EPMC97076013634727010.3201/eid2812.221304