biostudies-literatureUnknown23(12)Hagedoorn NN<h4>Objectives</h4>We aimed to describe the variation of hemostasis proteins in children with bacterial infections due to different pathogens ( Neisseria meningitidis, Streptococcus pneumoniae, Staphylococcus aureus , and group A streptococcus [GAS]) and to study hemostasis proteins in relation to mortality.<h4>Design</h4>Preplanned analysis in prospective cohort study.<h4>Setting</h4>Hospitals in five European countries (Austria, The Netherlands, Spain, Switzerland, and the United Kingdom).<h4>Patients</h4>Admitted children (2012-2016) with community-acquired infections due to meningococci ( n = 83), pneumococci ( n = 64), S. aureus (n = 50), and GAS ( n = 44) with available serum samples collected less than 48 hours after admission.<h4>Interventions</h4>None.<h4>Measurements and main resPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societiese543-e554https://www.ebi.ac.uk/biostudies/studies/S-EPMC9708080biostudies-literatureHemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study.PMC9708080Hagedoorn NNvan der Flier MVermont CDik WAHazelzet Jvan Rijswijk AAnderson SKohlfuerst DSKuijpers THerberg JLevin MCarrol EDEmonts MEuropean Union Childhood Life-threatening Infectious Disease (EUCLIDS) ConsortiumDriessen GSchlapbach LJZenz WBoeddha NPMartinon-Torres FAgapow PfalseHemostasis Proteins in Invasive Meningococcal and Nonmeningococcal Infections: A Prospective Multicenter Study.<h4>Objectives</h4>We aimed to describe the variation of hemostasis proteins in children with bacterial infections due to different pathogens ( Neisseria meningitidis, Streptococcus pneumoniae, Staphylococcus aureus , and group A streptococcus [GAS]) and to study hemostasis proteins in relation to mortality.<h4>Design</h4>Preplanned analysis in prospective cohort study.<h4>Setting</h4>Hospitals in five European countries (Austria, The Netherlands, Spain, Switzerland, and the United Kingdom).<h4>Patients</h4>Admitted children (2012-2016) with community-acquired infections due to meningococci ( n = 83), pneumococci ( n = 64), S. aureus (n = 50), and GAS ( n = 44) with available serum samples collected less than 48 hours after admission.<h4>Interventions</h4>None.<h4>Measurements and main res2022-01-01T00:00:00Z2022 Dec2025-04-05T11:48:34.274Z2025-04-05T11:48:34.274ZS-EPMC97080803604431310.1097/PCC.0000000000003056