{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8(12)"],"submitter":["Bechara R"],"pubmed_abstract":["Anaerobic digestion is a sustainable organic waste treatment technique with energy recovery via biogas generation. This work presents a novel Aspen Plus ADM1-based flowsheet for this process. Three reactor segments were chosen: stoichiometric for the hydrolysis step, kinetic for acido-aceto-methanogenesis, and equilibrium for hydrogenotrophic methane production. Selected parameters- conversion ratios, kinetic pre-exponent and inhibitor factors- were controlled to best fit model and experimental results. The parity plot fitting had an R<sup>2</sup> = 0.999, a slope of 1.0058 and an intercept of -0.8651. Obtained parameter values stressed the importance of inhibitions, and simulation results showcased the bell-shaped curve for acetic and volatile fatty acid reduction. The model was used for a subsequent sensitivity analysis as well as an optimization runs, leading to a 50% higher methane production ratio. The proposed model presents itself as a significant contribution for optimal anaerobic digestion process design."],"journal":["Heliyon"],"pagination":["e11793"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9712131"],"repository":["biostudies-literature"],"pubmed_title":["Improvements to the ADM1 based Process Simulation Model: Reaction segregation, parameter estimation and process optimization."],"pmcid":["PMC9712131"],"pubmed_authors":["Bechara R"],"additional_accession":[]},"is_claimable":false,"name":"Improvements to the ADM1 based Process Simulation Model: Reaction segregation, parameter estimation and process optimization.","description":"Anaerobic digestion is a sustainable organic waste treatment technique with energy recovery via biogas generation. This work presents a novel Aspen Plus ADM1-based flowsheet for this process. Three reactor segments were chosen: stoichiometric for the hydrolysis step, kinetic for acido-aceto-methanogenesis, and equilibrium for hydrogenotrophic methane production. Selected parameters- conversion ratios, kinetic pre-exponent and inhibitor factors- were controlled to best fit model and experimental results. The parity plot fitting had an R<sup>2</sup> = 0.999, a slope of 1.0058 and an intercept of -0.8651. Obtained parameter values stressed the importance of inhibitions, and simulation results showcased the bell-shaped curve for acetic and volatile fatty acid reduction. The model was used for a subsequent sensitivity analysis as well as an optimization runs, leading to a 50% higher methane production ratio. The proposed model presents itself as a significant contribution for optimal anaerobic digestion process design.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-04T23:44:55.762Z","creation":"2025-04-04T23:44:55.762Z"},"accession":"S-EPMC9712131","cross_references":{"pubmed":["36466570"],"doi":["10.1016/j.heliyon.2022.e11793"]}}