{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ruf CG"],"funding":["70112789"],"pagination":["2889-2900"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9712330"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["40(12)"],"pubmed_abstract":["<h4>Purpose</h4>Testicular germ cell tumours (GCTs) represent the most common malignancy in young adult males with two thirds of all cases presenting with clinical stage I (CSI). Active surveillance is the management modality mostly favoured by current guidelines. This systematic review assesses the treatment results in CSI patients concerning recurrence rate and overall survival in non-seminoma (NS) and pure seminoma (SE) resulting from surveillance in comparison to adjuvant strategies.<h4>Methods/systematic review</h4>We performed a systematic literature review confining the search to most recent studies published 2010-2021 that reported direct comparisons of surveillance to adjuvant management. We searched Medline and the Cochrane Library with additional hand-searching of reference list"],"journal":["World journal of urology"],"pubmed_title":["Testicular germ cell tumours' clinical stage I: comparison of surveillance with adjuvant treatment strategies regarding recurrence rates and overall survival-a systematic review."],"pmcid":["PMC9712330"],"funding_grant_id":["70112789"],"pubmed_authors":["Oechsle K","Zengerling F","Lackner J","Busch J","Heinzelbecker J","Ruf CG","Dieckmann KP","Albers P","Winter C","Schmidt S","Krege S","Kliesch S","Oing C","Pfister D"],"additional_accession":[]},"is_claimable":false,"name":"Testicular germ cell tumours' clinical stage I: comparison of surveillance with adjuvant treatment strategies regarding recurrence rates and overall survival-a systematic review.","description":"<h4>Purpose</h4>Testicular germ cell tumours (GCTs) represent the most common malignancy in young adult males with two thirds of all cases presenting with clinical stage I (CSI). Active surveillance is the management modality mostly favoured by current guidelines. This systematic review assesses the treatment results in CSI patients concerning recurrence rate and overall survival in non-seminoma (NS) and pure seminoma (SE) resulting from surveillance in comparison to adjuvant strategies.<h4>Methods/systematic review</h4>We performed a systematic literature review confining the search to most recent studies published 2010-2021 that reported direct comparisons of surveillance to adjuvant management. We searched Medline and the Cochrane Library with additional hand-searching of reference list","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-18T22:26:33.898Z","creation":"2025-04-07T10:09:49.205Z"},"accession":"S-EPMC9712330","cross_references":{"pubmed":["36107211"],"doi":["10.1007/s00345-022-04145-6"]}}