biostudies-literatureUnknown38(5)Williams CP<h4>Background</h4>People experiencing financial burden are underrepresented in clinical trials.<h4>Objective</h4>Describe the prevalence of cost-related considerations influential to trial participation and their associations with person-level characteristics.<h4>Design</h4>This cross-sectional study used and assessed how three cost-related considerations would influence the decision to participate in a hypothetical clinical trial.<h4>Participants</h4>A total of 3682 US adult respondents to the Health Information National Trends Survey MAIN MEASURES: Survey-weighted multivariable logistic regression estimated associations between respondent characteristics and odds of reporting cost-related considerations as very influential to participation.<h4>Key results</h4>Among 3682 respondents, medJournal of general internal medicine1200-1206https://www.ebi.ac.uk/biostudies/studies/S-EPMC9713084biostudies-literatureInfluence of Cost-Related Considerations on Clinical Trial Participation: Results from the 2020 Health Information National Trends Survey (HINTS).PMC9713084Williams CPGeiger AMde Moor JSEverson NSNorton WEfalseInfluence of Cost-Related Considerations on Clinical Trial Participation: Results from the 2020 Health Information National Trends Survey (HINTS).<h4>Background</h4>People experiencing financial burden are underrepresented in clinical trials.<h4>Objective</h4>Describe the prevalence of cost-related considerations influential to trial participation and their associations with person-level characteristics.<h4>Design</h4>This cross-sectional study used and assessed how three cost-related considerations would influence the decision to participate in a hypothetical clinical trial.<h4>Participants</h4>A total of 3682 US adult respondents to the Health Information National Trends Survey MAIN MEASURES: Survey-weighted multivariable logistic regression estimated associations between respondent characteristics and odds of reporting cost-related considerations as very influential to participation.<h4>Key results</h4>Among 3682 respondents, med2023-01-01T00:00:00Z2023 Apr2025-04-27T02:37:03.685Z2025-04-06T18:37:36.967ZS-EPMC97130843645101610.1007/s11606-022-07801-0