biostudies-literatureUnknown10(1)Palomo A<h4>Background</h4>The discovery of microorganisms capable of complete ammonia oxidation to nitrate (comammox) has prompted a paradigm shift in our understanding of nitrification, an essential process in N cycling, hitherto considered to require both ammonia oxidizing and nitrite oxidizing microorganisms. This intriguing metabolism is unique to the genus Nitrospira, a diverse taxon previously known to only contain canonical nitrite oxidizers. Comammox Nitrospira have been detected in diverse environments; however, a global view of the distribution, abundance, and diversity of Nitrospira species is still incomplete.<h4>Results</h4>In this study, we retrieved 55 metagenome-assembled Nitrospira genomes (MAGs) from newly obtained and publicly available metagenomes. Combined with publicly availMicrobiome204https://www.ebi.ac.uk/biostudies/studies/S-EPMC9714041biostudies-literatureGenomic profiling of Nitrospira species reveals ecological success of comammox Nitrospira.PMC9714041Palomo ADechesne ASmets BFPedersen AGfalseGenomic profiling of Nitrospira species reveals ecological success of comammox Nitrospira.<h4>Background</h4>The discovery of microorganisms capable of complete ammonia oxidation to nitrate (comammox) has prompted a paradigm shift in our understanding of nitrification, an essential process in N cycling, hitherto considered to require both ammonia oxidizing and nitrite oxidizing microorganisms. This intriguing metabolism is unique to the genus Nitrospira, a diverse taxon previously known to only contain canonical nitrite oxidizers. Comammox Nitrospira have been detected in diverse environments; however, a global view of the distribution, abundance, and diversity of Nitrospira species is still incomplete.<h4>Results</h4>In this study, we retrieved 55 metagenome-assembled Nitrospira genomes (MAGs) from newly obtained and publicly available metagenomes. Combined with publicly avail2022-01-01T00:00:00Z2022 Nov2025-04-19T03:34:54.127Z2025-04-07T13:42:42.901ZS-EPMC97140413645124410.1186/s40168-022-01411-y