biostudies-literatureBraga ADonald P. Goldstein MD Trophoblastic Tumor Registry Endowment, the Dyett Family Trophoblastic Disease Research and Registry Endowment and Keith Higgins and the Andrea S. Higgins Research FundCarlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro – FAPERJNational Council for Scientific and Technological Development – CNPqe0277892https://www.ebi.ac.uk/biostudies/studies/S-EPMC9714693biostudies-literatureUnknown17(12)<h4>Objective</h4>To relate preevacuation platelet count and leukogram findings, especially neutrophil/lymphocyte ratios (NLR) and platelet/lymphocyte ratios with the occurrence of gestational trophoblastic neoplasia (GTN) after complete hydatidiform mole (CHM) among Brazilian women.<h4>Methods</h4>Retrospective cohort study of patients with CHM followed at Rio de Janeiro Federal University, from January/2015-December/2020. Before molar evacuation, all patients underwent a medical evaluation, complete blood count and hCG measurement, in addition to other routine preoperative tests. The primary outcome was the occurrence of postmolar GTN.<h4>Results</h4>From 827 cases of CHM treated initially at the Reference Center, 696 (84.15%) had spontaneous remission and 131 (15.85%) developed postmolaPloS oneNeutrophil/lymphocyte ratio and other blood cell component counts are not associated with the development of postmolar gestational trophoblastic neoplasia.PMC9714693E-26/201.166/20221311862/2020-9Maesta IBessel MBerkowitz RSElias KMRezende Filho JBraga AGiongo Pedrotti LVieira Dos Santos Esteves APAmim Junior JHorowitz NSCanelas ACTorres BfalseNeutrophil/lymphocyte ratio and other blood cell component counts are not associated with the development of postmolar gestational trophoblastic neoplasia.<h4>Objective</h4>To relate preevacuation platelet count and leukogram findings, especially neutrophil/lymphocyte ratios (NLR) and platelet/lymphocyte ratios with the occurrence of gestational trophoblastic neoplasia (GTN) after complete hydatidiform mole (CHM) among Brazilian women.<h4>Methods</h4>Retrospective cohort study of patients with CHM followed at Rio de Janeiro Federal University, from January/2015-December/2020. Before molar evacuation, all patients underwent a medical evaluation, complete blood count and hCG measurement, in addition to other routine preoperative tests. The primary outcome was the occurrence of postmolar GTN.<h4>Results</h4>From 827 cases of CHM treated initially at the Reference Center, 696 (84.15%) had spontaneous remission and 131 (15.85%) developed postmola2022-01-01T00:00:00Z20222025-04-21T23:17:47.775Z2025-04-05T19:06:51.66ZS-EPMC97146933645477810.1371/journal.pone.0277892