{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["DeJong M"],"funding":["Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (Conseil de Recherches en Sciences Naturelles et en Génie du Canada)","ACS | American Chemical Society Petroleum Research Fund (ACS Petroleum Research Fund)"],"pagination":["7407"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9715722"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["13(1)"],"pubmed_abstract":["Despite dominating industrial processes, heterogeneous catalysts remain challenging to characterize and control. This is largely attributable to the diversity of potentially active sites at the catalyst-reactant interface and the complex behaviour that can arise from interactions between active sites. Surface-supported, single-site molecular catalysts aim to bring together benefits of both heterogeneous and homogeneous catalysts, offering easy separability while exploiting molecular design of reactivity, though the presence of a surface is likely to influence reaction mechanisms. Here, we use metal-organic coordination to build reactive Fe-terpyridine sites on the Ag(111) surface and study their activity towards CO and C<sub>2</sub>H<sub>4</sub> gaseous reactants using low-temperature ultrahigh-vacuum scanning tunnelling microscopy, scanning tunnelling spectroscopy, and atomic force microscopy supported by density-functional theory models. Using a site-by-site approach at low temperature to visualize the reaction pathway, we find that reactants bond to the Fe-tpy active sites via surface-bound intermediates, and investigate the role of the substrate in understanding and designing single-site catalysts on metallic supports."],"journal":["Nature communications"],"pubmed_title":["Small molecule binding to surface-supported single-site transition-metal reaction centres."],"pmcid":["PMC9715722"],"funding_grant_id":["RGPIN-2018-04271","RGPIN-2016-05795","55955-ND5"],"pubmed_authors":["Price AJA","Burke SA","DeJong M","Marsell E","Tom G","Johnson ER","Nguyen GD"],"additional_accession":[]},"is_claimable":false,"name":"Small molecule binding to surface-supported single-site transition-metal reaction centres.","description":"Despite dominating industrial processes, heterogeneous catalysts remain challenging to characterize and control. This is largely attributable to the diversity of potentially active sites at the catalyst-reactant interface and the complex behaviour that can arise from interactions between active sites. Surface-supported, single-site molecular catalysts aim to bring together benefits of both heterogeneous and homogeneous catalysts, offering easy separability while exploiting molecular design of reactivity, though the presence of a surface is likely to influence reaction mechanisms. Here, we use metal-organic coordination to build reactive Fe-terpyridine sites on the Ag(111) surface and study their activity towards CO and C<sub>2</sub>H<sub>4</sub> gaseous reactants using low-temperature ultrahigh-vacuum scanning tunnelling microscopy, scanning tunnelling spectroscopy, and atomic force microscopy supported by density-functional theory models. Using a site-by-site approach at low temperature to visualize the reaction pathway, we find that reactants bond to the Fe-tpy active sites via surface-bound intermediates, and investigate the role of the substrate in understanding and designing single-site catalysts on metallic supports.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-26T12:33:04.088Z","creation":"2025-04-06T14:02:06.345Z"},"accession":"S-EPMC9715722","cross_references":{"pubmed":["36456555"],"doi":["10.1038/s41467-022-35193-6"]}}