biostudies-literatureHuang WMTaipei Veterans General HospitalMinistry of Health and WelfareConsejería de Salud y Bienestar Social, Junta de Andalucía2928-2936https://www.ebi.ac.uk/biostudies/studies/S-EPMC9715785biostudies-literatureUnknown9(5)<h4>Aims</h4>Impaired renal function (IRF) prevails in patients with acute heart failure. The study aimed to investigate the prevalence of on-admission IRF and its association with short-term and long-term mortalities in patients hospitalized for HF with reduced (HFrEF), mildly reduced (HFmrEF), and preserved (HFpEF) left ventricular ejection fraction (LVEF).<h4>Methods</h4>Patients hospitalized for acute heart failure were enrolled and stratified by LVEF into three phenotypes as HFpEF (≥50%), HFmrEF (40-49%), and HFrEF (<40%). IRF was defined as an estimated glomerular filtration rate of ≤60 mL/min/1.73m² on admission. National Death Registry was linked for the identification of mortality.<h4>Results</h4>Of 2613 patients enrolled, 673 (25.7%) had HFrEF, 367 (14.0%) had HFmrEF, ESC heart failureImpaired renal function and mortalities in acute heart failure with different phenotypes.PMC9715785V104C-172V110B‐032V110B-032V100C-145V104C‐172V101C‐092V100C‐145V101C-092V102C-119V108C-133MOHW-104-TDU-B-211-113003V108C‐133V103B‐017MOHW111‐TDU‐B‐211‐134001V102C‐119MOHW106‐TDU‐B‐211‐113001MOHW108‐TDU‐B‐211‐133001MOHW107‐TDU‐B‐211‐123001MOHW‐104‐TDU‐B‐211‐113003MOHW107-TDU-B-211-123001MOHW106-TDU-B-211-113001MOHW108-TDU-B-211-133001V107C‐027V107C-027MOHW‐105‐TDU‐B‐211‐133017MOHW111-TDU-B-211-134001V103B-017MOHW-105-TDU-B-211-133017Cheng HMSung SHLee CWHuang WMChiang CEHuang CJYu WCChang HCChen CHGuo CYfalseImpaired renal function and mortalities in acute heart failure with different phenotypes.<h4>Aims</h4>Impaired renal function (IRF) prevails in patients with acute heart failure. The study aimed to investigate the prevalence of on-admission IRF and its association with short-term and long-term mortalities in patients hospitalized for HF with reduced (HFrEF), mildly reduced (HFmrEF), and preserved (HFpEF) left ventricular ejection fraction (LVEF).<h4>Methods</h4>Patients hospitalized for acute heart failure were enrolled and stratified by LVEF into three phenotypes as HFpEF (≥50%), HFmrEF (40-49%), and HFrEF (<40%). IRF was defined as an estimated glomerular filtration rate of ≤60 mL/min/1.73m² on admission. National Death Registry was linked for the identification of mortality.<h4>Results</h4>Of 2613 patients enrolled, 673 (25.7%) had HFrEF, 367 (14.0%) had HFmrEF, 2022-01-01T00:00:00Z2022 Oct2026-07-14T17:11:06.486Z2025-04-06T16:31:27.333ZS-EPMC97157853571299210.1002/ehf2.14002