biostudies-literatureUnknown22(1)Hong Z<h4>Objective</h4>To understand the occurrence of atopic dermatitis (AD) in children aged 2 years on exposure to maternal group B streptococcus (GBS) antibiotic prophylaxis (IAP).<h4>Design</h4>Retrospective cohort study of 2909 mother-child pairs.<h4>Setting</h4>Taixing People's Hospital in Eastern China.<h4>Participants</h4>Term infants born 2018-2019, followed longitudinally from birth to 2 years.<h4>Exposures</h4>The GBS-IAP was defined as therapy with intravenous penicillin G or ampicillin or cefazolin ≥ 4 h prior to delivery to the mother. Reference infants were defined as born without or with other intrapartum antibiotic exposure.<h4>Outcomes</h4>The logistic regression models were employed to analyze the effect of intrapartum GBS prophylaxis on AD in 2-year-old children during deliBMC pediatrics693https://www.ebi.ac.uk/biostudies/studies/S-EPMC9716662biostudies-literatureA cohort study of intrapartum group B streptococcus prophylaxis on atopic dermatitis in 2-year-old children.PMC9716662Yang WKang XHui LHong ZBaojian ZXin DXiaoping YJing RChunmei ZfalseA cohort study of intrapartum group B streptococcus prophylaxis on atopic dermatitis in 2-year-old children.<h4>Objective</h4>To understand the occurrence of atopic dermatitis (AD) in children aged 2 years on exposure to maternal group B streptococcus (GBS) antibiotic prophylaxis (IAP).<h4>Design</h4>Retrospective cohort study of 2909 mother-child pairs.<h4>Setting</h4>Taixing People's Hospital in Eastern China.<h4>Participants</h4>Term infants born 2018-2019, followed longitudinally from birth to 2 years.<h4>Exposures</h4>The GBS-IAP was defined as therapy with intravenous penicillin G or ampicillin or cefazolin ≥ 4 h prior to delivery to the mother. Reference infants were defined as born without or with other intrapartum antibiotic exposure.<h4>Outcomes</h4>The logistic regression models were employed to analyze the effect of intrapartum GBS prophylaxis on AD in 2-year-old children during deli2022-01-01T00:00:00Z2022 Dec2025-04-18T17:15:19.037Z2025-02-19T01:57:39.401ZS-EPMC97166623646097510.1186/s12887-022-03758-5