{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["3(10)"],"submitter":["Valentini N"],"pubmed_abstract":["Patients receiving hemodialysis (HD) have more inflammatory monocytes and less plasmacytoid dendritic cells (DCs) compared with healthy controls.Patients on HD who have a poor antibody response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine had fewer monocyte-derived DCs and conventional DCs compared with good responders.The defects in antigen presentation might be possible therapeutic targets to increase vaccine efficacy in HD patients."],"journal":["Kidney360"],"pagination":["1763-1768"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9717667"],"repository":["biostudies-literature"],"pubmed_title":["Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients."],"pmcid":["PMC9717667"],"pubmed_authors":["Valentini N","Raymond M","Finzi A","Kaufmann DE","Goyette G","Suri RS","Marchitto L","Lamarche C"],"additional_accession":[]},"is_claimable":false,"name":"Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients.","description":"Patients receiving hemodialysis (HD) have more inflammatory monocytes and less plasmacytoid dendritic cells (DCs) compared with healthy controls.Patients on HD who have a poor antibody response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine had fewer monocyte-derived DCs and conventional DCs compared with good responders.The defects in antigen presentation might be possible therapeutic targets to increase vaccine efficacy in HD patients.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Oct","modification":"2025-04-04T23:42:37.967Z","creation":"2025-04-04T23:42:37.967Z"},"accession":"S-EPMC9717667","cross_references":{"pubmed":["36514720"],"doi":["10.34067/KID.0002542022","10.34067/kid.0002542022"]}}