biostudies-literatureUnknown3(10)Valentini NPatients receiving hemodialysis (HD) have more inflammatory monocytes and less plasmacytoid dendritic cells (DCs) compared with healthy controls.Patients on HD who have a poor antibody response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine had fewer monocyte-derived DCs and conventional DCs compared with good responders.The defects in antigen presentation might be possible therapeutic targets to increase vaccine efficacy in HD patients.Kidney3601763-1768https://www.ebi.ac.uk/biostudies/studies/S-EPMC9717667biostudies-literatureInnate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients.PMC9717667Valentini NRaymond MFinzi AKaufmann DEGoyette GSuri RSMarchitto LLamarche CfalseInnate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients.Patients receiving hemodialysis (HD) have more inflammatory monocytes and less plasmacytoid dendritic cells (DCs) compared with healthy controls.Patients on HD who have a poor antibody response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine had fewer monocyte-derived DCs and conventional DCs compared with good responders.The defects in antigen presentation might be possible therapeutic targets to increase vaccine efficacy in HD patients.2022-01-01T00:00:00Z2022 Oct2025-04-04T23:42:37.967Z2025-04-04T23:42:37.967ZS-EPMC97176673651472010.34067/KID.000254202210.34067/kid.0002542022