{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Bera A"],"funding":["Science and Engineering Research Board","Council of Scientific and Industrial Research","Department of Biotechnology , Ministry of Science and Technology","Department of Science and Technology, Ministry of Science and Technology"],"pagination":["171-178"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9718314"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["2(3)"],"pubmed_abstract":["We demonstrate experimental evidence of the effect of surface plasmon resonance of noble metal nanoparticles (NPs) on the activity of a well-known biomedicinal drug in the proximity of a semiconductor having a wide band gap for enhanced photodynamic therapy (PDT) efficacy. We have chosen riboflavin (Rf) (or vitamin B<sub>2</sub>) as a model photosensitizer, attached with ZnO NPs and further attached with gold (Au) NP-decorated ZnO to increase the efficiency. The synthesized nanohybrids are characterized with the help of different microscopic, optical spectroscopic, and density functional theory (DFT)-based techniques. The DFT and time-dependent DFT-based calculations validate the experimental findings. A detailed ultrafast spectroscopic study has been carried out further to study the excit"],"journal":["ACS physical chemistry Au"],"pubmed_title":["Dual Sensitization via Electron and Energy Harvesting in a Nanohybrid for Improvement of Therapeutic Efficacy."],"pmcid":["PMC9718314"],"funding_grant_id":["DBT-BT/PR11534/NNT/28/766/2014","EMR/2016/ 004698","INAE/121/ AKF"],"pubmed_authors":["Pal SK","Bera A","Chatterjee A","Hasan MN","Mukherjee D"],"additional_accession":[]},"is_claimable":false,"name":"Dual Sensitization via Electron and Energy Harvesting in a Nanohybrid for Improvement of Therapeutic Efficacy.","description":"We demonstrate experimental evidence of the effect of surface plasmon resonance of noble metal nanoparticles (NPs) on the activity of a well-known biomedicinal drug in the proximity of a semiconductor having a wide band gap for enhanced photodynamic therapy (PDT) efficacy. We have chosen riboflavin (Rf) (or vitamin B<sub>2</sub>) as a model photosensitizer, attached with ZnO NPs and further attached with gold (Au) NP-decorated ZnO to increase the efficiency. The synthesized nanohybrids are characterized with the help of different microscopic, optical spectroscopic, and density functional theory (DFT)-based techniques. The DFT and time-dependent DFT-based calculations validate the experimental findings. A detailed ultrafast spectroscopic study has been carried out further to study the excit","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 May","modification":"2026-05-29T20:17:22.938Z","creation":"2025-04-07T00:31:45.971Z"},"accession":"S-EPMC9718314","cross_references":{"pubmed":["36855571"],"doi":["10.1021/acsphyschemau.1c00033"]}}