biostudies-literatureUnknown2022Zhang HKey Technology Research and Development Program of ShandongNational Basic Research Program of China (973 Program)Traditional Chinese Medicine In Colleges and Universities of Shandong ProvinceYinqiao powder, with significant anti‐inflammatory and antiviral effects, is a classical formula for the treatment of febrile diseases in China. During the SARS period in 2003, Yinqiao powder showed a good antipyretic effect. It also plays a major role in the treatment for COVID-19 in China. Although there are many studies on the chemical compositions and pharmacological effects of Yinqiao powder, there are few studies on the quality standard system of it. In our study, a systematic quality evaluation method of Yinqiao powder combining HPLC fingerprint with quantitative analysis of multi-components by single marker (QAMS) based on network pharmacology and UPLC-Q-Exactive-Orbitrap-MS was established for the first time. In the UPLC-Q-Exactive-Orbitrap-MS experiment, a total of 53 compounds wJournal of Analytical Methods in Chemistryhttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9718632biostudies-literatureEstablishment of Quality Evaluation Method for Yinqiao Powder: A Herbal Formula against COVID-19 in ChinaPMC97186322018GSF1190182019YFE0117800CYLXTCX2021-01Xu LWang PZhang HZhang XLi QQu XSong JZhang AfalseEstablishment of Quality Evaluation Method for Yinqiao Powder: A Herbal Formula against COVID-19 in ChinaYinqiao powder, with significant anti‐inflammatory and antiviral effects, is a classical formula for the treatment of febrile diseases in China. During the SARS period in 2003, Yinqiao powder showed a good antipyretic effect. It also plays a major role in the treatment for COVID-19 in China. Although there are many studies on the chemical compositions and pharmacological effects of Yinqiao powder, there are few studies on the quality standard system of it. In our study, a systematic quality evaluation method of Yinqiao powder combining HPLC fingerprint with quantitative analysis of multi-components by single marker (QAMS) based on network pharmacology and UPLC-Q-Exactive-Orbitrap-MS was established for the first time. In the UPLC-Q-Exactive-Orbitrap-MS experiment, a total of 53 compounds w2022-01-01T00:00:00Z2022 Jan2025-04-04T07:48:05.247Z2025-02-19T04:13:45.374ZS-EPMC9718632