{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Ikegaya N"],"funding":["NINDS NIH HHS","NIH"],"pagination":["1446-1454"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9724167"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["130(8)"],"pubmed_abstract":["<h4>Objective</h4>To characterize the spatiotemporal dynamics of auditory and picture naming-related cortical activation in Japanese-speaking patients.<h4>Methods</h4>Ten patients were assigned auditory naming and picture naming tasks during extraoperative intracranial EEG recording in a tertiary epilepsy center. Time-frequency analysis determined at what electrode sites and at what time windows during each task the amplitude of high-gamma activity (65-95 Hz) was modulated.<h4>Results</h4>The superior-temporal gyrus on each hemisphere showed high-gamma augmentation during sentence listening, whereas the left middle-temporal and inferior-frontal gyri showed high-gamma augmentation peaking around stimulus offset. Auditory naming-specific high-gamma augmentation was noted in the bilateral superior-temporal gyri as well as left frontal-parietal-temporal perisylvian network regions, whereas picture naming-specific augmentation was noted in the occipital-fusiform regions, bilaterally. The inferior pre- and postcentral gyri on each hemisphere showed modality-common high-gamma augmentation time-locked to overt responses.<h4>Conclusions</h4>The spatiotemporal dynamics of auditory and picture naming-related high-gamma augmentation in Japanese-speaking patients were qualitatively similar to those previously reported in studies of English-speaking patients.<h4>Significance</h4>The cortical dynamics for auditory sentence recognition are at least partly shared by cohorts speaking two distinct languages. Multicenter studies regarding the clinical utility of high-gamma language mapping across Eastern and Western hemispheres may be feasible."],"journal":["Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology"],"pubmed_title":["Spatiotemporal dynamics of auditory and picture naming-related high-gamma modulations: A study of Japanese-speaking patients."],"pmcid":["PMC9724167"],"funding_grant_id":["R01 NS064033","NS064033"],"pubmed_authors":["Motoi H","Kambara T","Silverstein BH","Asano E","Ikegaya N","Takayama Y","Iijima K","Iwasaki M","Sugiura A"],"additional_accession":[]},"is_claimable":false,"name":"Spatiotemporal dynamics of auditory and picture naming-related high-gamma modulations: A study of Japanese-speaking patients.","description":"<h4>Objective</h4>To characterize the spatiotemporal dynamics of auditory and picture naming-related cortical activation in Japanese-speaking patients.<h4>Methods</h4>Ten patients were assigned auditory naming and picture naming tasks during extraoperative intracranial EEG recording in a tertiary epilepsy center. Time-frequency analysis determined at what electrode sites and at what time windows during each task the amplitude of high-gamma activity (65-95 Hz) was modulated.<h4>Results</h4>The superior-temporal gyrus on each hemisphere showed high-gamma augmentation during sentence listening, whereas the left middle-temporal and inferior-frontal gyri showed high-gamma augmentation peaking around stimulus offset. Auditory naming-specific high-gamma augmentation was noted in the bilateral superior-temporal gyri as well as left frontal-parietal-temporal perisylvian network regions, whereas picture naming-specific augmentation was noted in the occipital-fusiform regions, bilaterally. The inferior pre- and postcentral gyri on each hemisphere showed modality-common high-gamma augmentation time-locked to overt responses.<h4>Conclusions</h4>The spatiotemporal dynamics of auditory and picture naming-related high-gamma augmentation in Japanese-speaking patients were qualitatively similar to those previously reported in studies of English-speaking patients.<h4>Significance</h4>The cortical dynamics for auditory sentence recognition are at least partly shared by cohorts speaking two distinct languages. Multicenter studies regarding the clinical utility of high-gamma language mapping across Eastern and Western hemispheres may be feasible.","dates":{"release":"2019-01-01T00:00:00Z","publication":"2019 Aug","modification":"2025-04-26T02:10:17.981Z","creation":"2025-04-06T10:24:04.076Z"},"accession":"S-EPMC9724167","cross_references":{"pubmed":["31056408"],"doi":["10.1016/j.clinph.2019.04.008"]}}