biostudies-literatureIkegaya NNINDS NIH HHSNIH1446-1454https://www.ebi.ac.uk/biostudies/studies/S-EPMC9724167biostudies-literatureUnknown130(8)<h4>Objective</h4>To characterize the spatiotemporal dynamics of auditory and picture naming-related cortical activation in Japanese-speaking patients.<h4>Methods</h4>Ten patients were assigned auditory naming and picture naming tasks during extraoperative intracranial EEG recording in a tertiary epilepsy center. Time-frequency analysis determined at what electrode sites and at what time windows during each task the amplitude of high-gamma activity (65-95 Hz) was modulated.<h4>Results</h4>The superior-temporal gyrus on each hemisphere showed high-gamma augmentation during sentence listening, whereas the left middle-temporal and inferior-frontal gyri showed high-gamma augmentation peaking around stimulus offset. Auditory naming-specific high-gamma augmentation was noted in the bilateral superior-temporal gyri as well as left frontal-parietal-temporal perisylvian network regions, whereas picture naming-specific augmentation was noted in the occipital-fusiform regions, bilaterally. The inferior pre- and postcentral gyri on each hemisphere showed modality-common high-gamma augmentation time-locked to overt responses.<h4>Conclusions</h4>The spatiotemporal dynamics of auditory and picture naming-related high-gamma augmentation in Japanese-speaking patients were qualitatively similar to those previously reported in studies of English-speaking patients.<h4>Significance</h4>The cortical dynamics for auditory sentence recognition are at least partly shared by cohorts speaking two distinct languages. Multicenter studies regarding the clinical utility of high-gamma language mapping across Eastern and Western hemispheres may be feasible.Clinical neurophysiology : official journal of the International Federation of Clinical NeurophysiologySpatiotemporal dynamics of auditory and picture naming-related high-gamma modulations: A study of Japanese-speaking patients.PMC9724167R01 NS064033NS064033Motoi HKambara TSilverstein BHAsano EIkegaya NTakayama YIijima KIwasaki MSugiura AfalseSpatiotemporal dynamics of auditory and picture naming-related high-gamma modulations: A study of Japanese-speaking patients.<h4>Objective</h4>To characterize the spatiotemporal dynamics of auditory and picture naming-related cortical activation in Japanese-speaking patients.<h4>Methods</h4>Ten patients were assigned auditory naming and picture naming tasks during extraoperative intracranial EEG recording in a tertiary epilepsy center. Time-frequency analysis determined at what electrode sites and at what time windows during each task the amplitude of high-gamma activity (65-95 Hz) was modulated.<h4>Results</h4>The superior-temporal gyrus on each hemisphere showed high-gamma augmentation during sentence listening, whereas the left middle-temporal and inferior-frontal gyri showed high-gamma augmentation peaking around stimulus offset. Auditory naming-specific high-gamma augmentation was noted in the bilateral superior-temporal gyri as well as left frontal-parietal-temporal perisylvian network regions, whereas picture naming-specific augmentation was noted in the occipital-fusiform regions, bilaterally. The inferior pre- and postcentral gyri on each hemisphere showed modality-common high-gamma augmentation time-locked to overt responses.<h4>Conclusions</h4>The spatiotemporal dynamics of auditory and picture naming-related high-gamma augmentation in Japanese-speaking patients were qualitatively similar to those previously reported in studies of English-speaking patients.<h4>Significance</h4>The cortical dynamics for auditory sentence recognition are at least partly shared by cohorts speaking two distinct languages. Multicenter studies regarding the clinical utility of high-gamma language mapping across Eastern and Western hemispheres may be feasible.2019-01-01T00:00:00Z2019 Aug2025-04-26T02:10:17.981Z2025-04-06T10:24:04.076ZS-EPMC97241673105640810.1016/j.clinph.2019.04.008