biostudies-literatureMaznyczka AMBritish Heart FoundationMedical Research CouncilChief Scientist Office220-228https://www.ebi.ac.uk/biostudies/studies/S-EPMC9724875biostudies-literatureUnknown17(3)<h4>Background</h4>Novel parameters that detect failed microvascular reperfusion might identify better the patients likely to benefit from adjunctive treatments during primary percutaneous coronary intervention (PCI).<h4>Aims</h4>The aim of this study was to test the hypothesis that a novel invasive parameter, the thermodilution-derived temperature recovery time (TRT), would be associated with microvascular obstruction (MVO) and prognosis.<h4>Methods</h4>TRT was derived and validated in two independent ST-elevation myocardial infarction populations and was measured immediately post PCI. TRT was defined as the duration (seconds) from the nadir of the hyperaemic thermodilution curve to 20% from baseline body temperature. MVO extent (% left ventricular mass) was assessed by cardiovascular magEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of CardiologyThermodilution-derived temperature recovery time: a novel predictor of microvascular reperfusion and prognosis after myocardial infarction.PMC9724875MC_PC_15113PG/11/55/28999PG/14/64/31043RE/13/5/30177FS/16/74/32573MR/N003403/1MC_PC_12037SCD/01PG/11/2/28474James-Rae GGreenwood JPCotton JMOldroyd KGEteiba HBerry CPetrie MCLindsay MMCarrick DGood RMcEntegart MMaznyczka AMMcCartney PfalseThermodilution-derived temperature recovery time: a novel predictor of microvascular reperfusion and prognosis after myocardial infarction.<h4>Background</h4>Novel parameters that detect failed microvascular reperfusion might identify better the patients likely to benefit from adjunctive treatments during primary percutaneous coronary intervention (PCI).<h4>Aims</h4>The aim of this study was to test the hypothesis that a novel invasive parameter, the thermodilution-derived temperature recovery time (TRT), would be associated with microvascular obstruction (MVO) and prognosis.<h4>Methods</h4>TRT was derived and validated in two independent ST-elevation myocardial infarction populations and was measured immediately post PCI. TRT was defined as the duration (seconds) from the nadir of the hyperaemic thermodilution curve to 20% from baseline body temperature. MVO extent (% left ventricular mass) was assessed by cardiovascular mag2021-01-01T00:00:00Z2021 Jun2026-05-28T06:07:29.385Z2024-11-19T16:26:48.104ZS-EPMC97248753212282210.4244/eij-d-19-0090410.4244/EIJ-D-19-00904