{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(8)"],"submitter":["Guo J"],"pubmed_abstract":["<h4>Background</h4>Early spontaneous reperfusion (ESR) is not an uncommon phenomenon in clinical settings.<h4>Aims</h4>The aim of this study was to detect potential mechanisms of ESR in patients with STEMI.<h4>Methods</h4>This prospective study enrolled a total of 241 consecutive patients with STEMI undergoing optical coherence tomography (OCT) from July 2016 to August 2019. Forty-five patients (18.7%) met angiographic ESR criteria (TIMI 3 flow on the initial angiogram). Among those without ESR (TIMI 0 flow on initial angiogram), 45 patients were assigned to the control group according to propensity score matching with the ESR group.<h4>Results</h4>Although the baseline characteristics of the groups were comparable, non-ruptured plaque (62.2% vs 35.6%) predominated and plaque rupture (37.8% vs 64.4%) was less common in the ESR group (p=0.011). Red thrombus (44.4% vs 77.8%) was also less common in the ESR group (p=0.001). Lastly, compared to the control group, the ESR group underwent fewer emergent stent placements (68.9% vs 91.1%, p=0.008).<h4>Conclusions</h4>Relief of coronary occlusion induced by a non-ruptured plaque may contribute to ESR in patients with STEMI."],"journal":["EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology"],"pagination":["e664-e671"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9724883"],"repository":["biostudies-literature"],"pubmed_title":["Plaque characteristics in patients with ST-segment elevation myocardial infarction and early spontaneous reperfusion."],"pmcid":["PMC9724883"],"pubmed_authors":["Shi N","Niu D","Li J","Chen J","Fan Z","Si J","Zuo X","Gao J","Wang G","Bai Z","Zhang L","Song J","Liu Z","Guo J","Zhang Y","Liu B","Wu Y","Miao Z"],"additional_accession":[]},"is_claimable":false,"name":"Plaque characteristics in patients with ST-segment elevation myocardial infarction and early spontaneous reperfusion.","description":"<h4>Background</h4>Early spontaneous reperfusion (ESR) is not an uncommon phenomenon in clinical settings.<h4>Aims</h4>The aim of this study was to detect potential mechanisms of ESR in patients with STEMI.<h4>Methods</h4>This prospective study enrolled a total of 241 consecutive patients with STEMI undergoing optical coherence tomography (OCT) from July 2016 to August 2019. Forty-five patients (18.7%) met angiographic ESR criteria (TIMI 3 flow on the initial angiogram). Among those without ESR (TIMI 0 flow on initial angiogram), 45 patients were assigned to the control group according to propensity score matching with the ESR group.<h4>Results</h4>Although the baseline characteristics of the groups were comparable, non-ruptured plaque (62.2% vs 35.6%) predominated and plaque rupture (37.8% vs 64.4%) was less common in the ESR group (p=0.011). Red thrombus (44.4% vs 77.8%) was also less common in the ESR group (p=0.001). Lastly, compared to the control group, the ESR group underwent fewer emergent stent placements (68.9% vs 91.1%, p=0.008).<h4>Conclusions</h4>Relief of coronary occlusion induced by a non-ruptured plaque may contribute to ESR in patients with STEMI.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Oct","modification":"2025-04-05T11:31:57.344Z","creation":"2025-04-05T11:31:57.344Z"},"accession":"S-EPMC9724883","cross_references":{"pubmed":["33495143"],"doi":["10.4244/EIJ-D-20-00812","10.4244/eij-d-20-00812"]}}