biostudies-literatureUnknown317Zhong WJohn S. and James L. Knight Foundation<h4>Objective</h4>To determine if framing communications about COVID-19 vaccines in economic terms can increase Republicans' likelihood to get vaccinated.<h4>Methods</h4>We examined Twitter posts between January 2020 and September 2021 by Democratic and Republican politicians to determine how they framed the COVID-19 pandemic. Based on these posts, we carried out a survey study between September and November 2021 to examine whether motivations for COVID-19 vaccine uptake matched message frames that were widely used by these politicians. Finally, we conducted a randomized controlled experiment to examine how these frames (economic vs. health) affected intentions to vaccinate by vaccine refusers in both parties.<h4>Results</h4>Republican politicians were more likely to frame the pandemic in Social science & medicine (1982)115594https://www.ebi.ac.uk/biostudies/studies/S-EPMC9726654biostudies-literatureEconomic risk framing increases intention to vaccinate among Republican COVID-19 vaccine refusers.PMC9726654Broniatowski DAZhong WfalseEconomic risk framing increases intention to vaccinate among Republican COVID-19 vaccine refusers.<h4>Objective</h4>To determine if framing communications about COVID-19 vaccines in economic terms can increase Republicans' likelihood to get vaccinated.<h4>Methods</h4>We examined Twitter posts between January 2020 and September 2021 by Democratic and Republican politicians to determine how they framed the COVID-19 pandemic. Based on these posts, we carried out a survey study between September and November 2021 to examine whether motivations for COVID-19 vaccine uptake matched message frames that were widely used by these politicians. Finally, we conducted a randomized controlled experiment to examine how these frames (economic vs. health) affected intentions to vaccinate by vaccine refusers in both parties.<h4>Results</h4>Republican politicians were more likely to frame the pandemic in 2023-01-01T00:00:00Z2023 Jan2026-05-28T00:39:23.946Z2025-02-18T22:51:35.029ZS-EPMC97266543650898910.1016/j.socscimed.2022.115594