biostudies-literatureUnknown14(1)Taieb ABNovo Nordisk A/S<h4>Background</h4>Obesity and overweight are major risk factors for several chronic diseases. There is limited systematic evaluation of risk equations that predict the likelihood of developing an obesity or overweight associated complication. Predicting future risk is essential for health economic modelling. Availability of future treatments rests upon a model's ability to inform clinical and decision-making bodies.  This systematic literature review aimed to identify studies reporting (1) equations that calculate the risk for individuals with obesity, or overweight with a weight-related complication (OWRC), of developing additional complications, namely T2D, cardiovascular (CV) disease (CVD), acute coronary syndrome, stroke, musculoskeletal disorders, knee replacement/arthroplasty, or obDiabetology & metabolic syndrome186https://www.ebi.ac.uk/biostudies/studies/S-EPMC9727983biostudies-literatureUnderstanding the risk of developing weight-related complications associated with different body mass index categories: a systematic review.PMC9727983Taieb ABLarsen SRoberts EWolfert DLuckevich Mle Roux CWde Freitas PGfalseUnderstanding the risk of developing weight-related complications associated with different body mass index categories: a systematic review.<h4>Background</h4>Obesity and overweight are major risk factors for several chronic diseases. There is limited systematic evaluation of risk equations that predict the likelihood of developing an obesity or overweight associated complication. Predicting future risk is essential for health economic modelling. Availability of future treatments rests upon a model's ability to inform clinical and decision-making bodies.  This systematic literature review aimed to identify studies reporting (1) equations that calculate the risk for individuals with obesity, or overweight with a weight-related complication (OWRC), of developing additional complications, namely T2D, cardiovascular (CV) disease (CVD), acute coronary syndrome, stroke, musculoskeletal disorders, knee replacement/arthroplasty, or ob2022-01-01T00:00:00Z2022 Dec2025-04-19T06:37:24.05Z2025-04-19T06:37:24.05ZS-EPMC97279833647623210.1186/s13098-022-00952-4