biostudies-literatureEtxandi MFEDER funds/European Regional Development FundDelegación del Gobierno para el Plan Nacional sobre DrogasNCATS NIH HHSInstituto de Salud Carlos IIIResearch Committee of the University Hospital of BellvitgeMinisterio de Ciencia, Innovación y UniversidadesConnecticut Council on Problem GamblingMinisterio de Ciencia, Innovación y Universidades, EspañaCatalan Institution for Research and Advanced Studies5084https://www.ebi.ac.uk/biostudies/studies/S-EPMC9736671biostudies-literatureUnknown14(23)Gambling disorder (GD) is a modestly prevalent and severe condition for which neurobiology is not yet fully understood. Although alterations in signals involved in energy homeostasis have been studied in substance use disorders, they have yet to be examined in detail in GD. The aims of the present study were to compare different endocrine and neuropsychological factors between individuals with GD and healthy controls (HC) and to explore endocrine interactions with neuropsychological and clinical variables. A case−control design was performed in 297 individuals with GD and 41 individuals without (healthy controls; HCs), assessed through a semi-structured clinical interview and a psychometric battery. For the evaluation of endocrine and anthropometric variables, 38 HCs were added to the 41 HNutrientsAre Signals Regulating Energy Homeostasis Related to Neuropsychological and Clinical Features of Gambling Disorder? A Case-Control Study.PMC9736671PI20/00132ICREA-AcademiaRTI2018-101837-B-100PI17/011672019I47 and 2021I031UL1 TR0018632021-Programme2019I47PI17/01167, PI20/001322021I031CM21/00172Post-ResidencyEtxandi MCasado SJimenez-Murcia SSole-Morata NDieguez CGomez-Pena MMoragas LFernandez-Aranda FPotenza MNGranero RCodina EPino-Gutierrez ADValenciano-Mendoza ELucas IMora-Maltas BBaenas ITovar SfalseAre Signals Regulating Energy Homeostasis Related to Neuropsychological and Clinical Features of Gambling Disorder? A Case-Control Study.Gambling disorder (GD) is a modestly prevalent and severe condition for which neurobiology is not yet fully understood. Although alterations in signals involved in energy homeostasis have been studied in substance use disorders, they have yet to be examined in detail in GD. The aims of the present study were to compare different endocrine and neuropsychological factors between individuals with GD and healthy controls (HC) and to explore endocrine interactions with neuropsychological and clinical variables. A case−control design was performed in 297 individuals with GD and 41 individuals without (healthy controls; HCs), assessed through a semi-structured clinical interview and a psychometric battery. For the evaluation of endocrine and anthropometric variables, 38 HCs were added to the 41 H2022-01-01T00:00:00Z2022 Nov2026-04-08T06:01:31.952Z2026-04-07T22:46:39.285ZS-EPMC97366713650111410.3390/nu14235084