{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Huang J"],"funding":["Guangxi Science and Technology Base Special Talents","the Natural Science Foundation of Guangxi Province","National Natural Science Foundation of China","Department of Science and Technology of Guangzhou"],"pagination":["8160"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9737011"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["27(23)"],"pubmed_abstract":["Chemical investigation of the fermentation extract of the mangrove endophytic fungus <i>Aspergillus</i> sp. GXNU-A1, isolated from <i>Acanthus ilicifolius</i> L., discovered an undescribed pair of enantiomers (asperphenyltones A and B (<b>±1</b>)), together with four previously described metabolites: nodulisporol (<b>2</b>), isosclerone (<b>3</b>), 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzyl alcohol (<b>4</b>), and 4,6-dihydroxy-5-methoxy-7-methyl-1,3-dihydroisobenzofuran (<b>5</b>). Analyses of the 1D and 2D NMR spectroscopic data of the compounds supported their structural assignments. The presence of the asperphenyltones A and B, which are a pair of enantiomers, was established by HR-ESI-MS, 1D and 2D NMR data and confirmed by single-crystal X-ray diffraction analysis. Metabolites"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Asperphenyltones A and B: New Phenylfuropyridinone Skeleton from an Endophytic <i>Aspergillus</i> sp. GXNU-A1."],"pmcid":["PMC9737011"],"funding_grant_id":["2020JJA150036","202102020608","2019AC20095","42066005"],"pubmed_authors":["Tan M","Huang J","Huang X","Bo X","Wu G","Wu F","Wei Y","Wang L","Zhou J"],"additional_accession":[]},"is_claimable":false,"name":"Asperphenyltones A and B: New Phenylfuropyridinone Skeleton from an Endophytic <i>Aspergillus</i> sp. GXNU-A1.","description":"Chemical investigation of the fermentation extract of the mangrove endophytic fungus <i>Aspergillus</i> sp. GXNU-A1, isolated from <i>Acanthus ilicifolius</i> L., discovered an undescribed pair of enantiomers (asperphenyltones A and B (<b>±1</b>)), together with four previously described metabolites: nodulisporol (<b>2</b>), isosclerone (<b>3</b>), 2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzyl alcohol (<b>4</b>), and 4,6-dihydroxy-5-methoxy-7-methyl-1,3-dihydroisobenzofuran (<b>5</b>). Analyses of the 1D and 2D NMR spectroscopic data of the compounds supported their structural assignments. The presence of the asperphenyltones A and B, which are a pair of enantiomers, was established by HR-ESI-MS, 1D and 2D NMR data and confirmed by single-crystal X-ray diffraction analysis. Metabolites","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2026-04-08T11:54:09.4Z","creation":"2024-11-15T04:20:27.063Z"},"accession":"S-EPMC9737011","cross_references":{"pubmed":["36500252"],"doi":["10.3390/molecules27238160"]}}