biostudies-literatureUnknown19(23)Kojic FThe present study investigated effects of squat resistance training on intermuscular hypertrophy of quadriceps femoris muscles (i.e., rectus femoris, RF; vastus intermedius, VI; vastus medialis, VM; and vastus lateralis, VL). Eighteen university students (age: 24.1 ± 1.7 years, 9 females) underwent 7 weeks of parallel squat training (2 days/week) preceded by a 2-week familiarization period. Squat strength (1RM) and cross-sectional area (CSA) of four quadriceps muscles were assessed at baseline and at the end of the study. At posttest, 1RM and CSA of quadriceps muscles significantly increased (p < 0.01), with moderate-to-large effect (ES = 1.25−2.11) for 1RM (8.33 ± 6.64 kg), VM CSA (0.12 ± 0.08 cm2), and VL CSA (0.19 ± 0.09 cm2) and small effect (ES = 0.89−1.13) for RF CSA (0.17 ± 0.15 cm2International journal of environmental research and public health16226https://www.ebi.ac.uk/biostudies/studies/S-EPMC9737272biostudies-literatureDoes Back Squat Exercise Lead to Regional Hypertrophy among Quadriceps Femoris Muscles?PMC9737272Kojic FPaloc MObradovic MMandic DDuric SPelemis VRanisavljev IfalseDoes Back Squat Exercise Lead to Regional Hypertrophy among Quadriceps Femoris Muscles?The present study investigated effects of squat resistance training on intermuscular hypertrophy of quadriceps femoris muscles (i.e., rectus femoris, RF; vastus intermedius, VI; vastus medialis, VM; and vastus lateralis, VL). Eighteen university students (age: 24.1 ± 1.7 years, 9 females) underwent 7 weeks of parallel squat training (2 days/week) preceded by a 2-week familiarization period. Squat strength (1RM) and cross-sectional area (CSA) of four quadriceps muscles were assessed at baseline and at the end of the study. At posttest, 1RM and CSA of quadriceps muscles significantly increased (p < 0.01), with moderate-to-large effect (ES = 1.25−2.11) for 1RM (8.33 ± 6.64 kg), VM CSA (0.12 ± 0.08 cm2), and VL CSA (0.19 ± 0.09 cm2) and small effect (ES = 0.89−1.13) for RF CSA (0.17 ± 0.15 cm22022-01-01T00:00:00Z2022 Dec2025-04-04T08:01:04.574Z2025-04-04T08:01:04.574ZS-EPMC97372723649829810.3390/ijerph192316226