{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(23)"],"submitter":["Pazzaglia C"],"pubmed_abstract":["The present study aims to investigate the benefits induced by physical activity/practiced sport in Charcot-Marie-Tooth 1A (CMT1A). Patients were divided into sport and no-sport groups according to their sports performance habit. Thirty-one patients were enrolled, of which 14 practiced sports and 17 did not. Clinical assessments were administered to evaluate disability, self-esteem, depression, quality of life, and pain. Statistical analysis revealed significant differences in terms of gender in the no-sport group compared to the sport group (p = 0.04). Regarding the quality of life, physical function (p = 0.001), general health (p = 0.03), social function (p = 0.04), and mental health (p = 0.006) showed better patterns in the sport group than no-sport group. Moreover, neuropathic pain was reduced in the sport group according to the Neuropathic Pain Symptom Inventory (p = 0.001) and ID-PAIN (p = 0.03). The other administered questionnaires showed no significant differences. Our study confirms that CMT1A patients, who practice sports, with a similar severity of disability, may have a better physical quality of life while suffering less neuropathic pain than their peers who do not practice sports. Results recommend the prescription of sport in CMT1A patients."],"journal":["Journal of clinical medicine"],"pagination":["7032"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9740468"],"repository":["biostudies-literature"],"pubmed_title":["Role of Sport Activity on Quality of Life in Charcot-Marie-Tooth 1A Patients."],"pmcid":["PMC9740468"],"pubmed_authors":["Castelli L","Vita GL","Loreti C","Coraci D","Imbimbo I","Vita G","Pazzaglia C","Giovannini S","Padua L","Stancanelli C","Fusco A"],"additional_accession":[]},"is_claimable":false,"name":"Role of Sport Activity on Quality of Life in Charcot-Marie-Tooth 1A Patients.","description":"The present study aims to investigate the benefits induced by physical activity/practiced sport in Charcot-Marie-Tooth 1A (CMT1A). Patients were divided into sport and no-sport groups according to their sports performance habit. Thirty-one patients were enrolled, of which 14 practiced sports and 17 did not. Clinical assessments were administered to evaluate disability, self-esteem, depression, quality of life, and pain. Statistical analysis revealed significant differences in terms of gender in the no-sport group compared to the sport group (p = 0.04). Regarding the quality of life, physical function (p = 0.001), general health (p = 0.03), social function (p = 0.04), and mental health (p = 0.006) showed better patterns in the sport group than no-sport group. Moreover, neuropathic pain was reduced in the sport group according to the Neuropathic Pain Symptom Inventory (p = 0.001) and ID-PAIN (p = 0.03). The other administered questionnaires showed no significant differences. Our study confirms that CMT1A patients, who practice sports, with a similar severity of disability, may have a better physical quality of life while suffering less neuropathic pain than their peers who do not practice sports. Results recommend the prescription of sport in CMT1A patients.","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Nov","modification":"2025-04-20T03:33:58.276Z","creation":"2025-04-20T03:33:58.276Z"},"accession":"S-EPMC9740468","cross_references":{"pubmed":["36498606"],"doi":["10.3390/jcm11237032"]}}