biostudies-literatureUnknownShokri Varniab Z<h4>Background</h4>Lung cancer is one of the leading cancers, with a high burden worldwide. As a developing country, Iran is facing with population growth, widespread tobacco use, demographic and epidemiologic changes, and environmental exposures, which lead to cancers becoming a severe concern of public health in Iran. We aimed to examine the burden of lung cancer and its risk factors in Iran.<h4>Methods</h4>We utilized the Global Burden of Disease 2019 data and analyzed the total burden of the lung cancer and seven related risk factors by sex, age at national and sub-national levels from 1990 to 2019.<h4>Results</h4>The lung cancer age-standardized death rate increased from 11.8 (95% Uncertainty Interval: 9.7-14.4) to 12.9 (11.9-13.9) per 100,000 between 1990 and 2019. This increase was Cancer medicinehttps://www.ebi.ac.uk/biostudies/studies/S-EPMC9741968biostudies-literatureEstimates of incidence, prevalence, mortality, and disability-adjusted life years of lung cancer in Iran, 1990-2019: A systematic analysis from the global burden of disease study 2019.PMC9741968Ghasemi ESharifnejad Tehrani YFarzadfar FRezaei NNamazi Shabestari AAzadnajafabad SGhamari AMalekpour MRShokri Varniab ZMohammadi Fateh SRashidi MMEsfahani ZPourabhari Langroudi ADilmaghani-Marand ALarijani BfalseEstimates of incidence, prevalence, mortality, and disability-adjusted life years of lung cancer in Iran, 1990-2019: A systematic analysis from the global burden of disease study 2019.<h4>Background</h4>Lung cancer is one of the leading cancers, with a high burden worldwide. As a developing country, Iran is facing with population growth, widespread tobacco use, demographic and epidemiologic changes, and environmental exposures, which lead to cancers becoming a severe concern of public health in Iran. We aimed to examine the burden of lung cancer and its risk factors in Iran.<h4>Methods</h4>We utilized the Global Burden of Disease 2019 data and analyzed the total burden of the lung cancer and seven related risk factors by sex, age at national and sub-national levels from 1990 to 2019.<h4>Results</h4>The lung cancer age-standardized death rate increased from 11.8 (95% Uncertainty Interval: 9.7-14.4) to 12.9 (11.9-13.9) per 100,000 between 1990 and 2019. This increase was 2022-01-01T00:00:00Z2022 Jun2025-05-29T16:30:11.618Z2025-05-29T16:30:11.618ZS-EPMC97419683569845110.1002/cam4.4792