biostudies-literatureUnknown9Gomez Gomez LCarotenoids are C40 isoprenoids with well-established roles in photosynthesis, pollination, photoprotection, and hormone biosynthesis. The enzymatic or ROS-induced cleavage of carotenoids generates a group of compounds named apocarotenoids, with an increasing interest by virtue of their metabolic, physiological, and ecological activities. Both classes are used industrially in a variety of fields as colorants, supplements, and bio-actives. Crocins and picrocrocin, two saffron apocarotenoids, are examples of high-value pigments utilized in the food, feed, and pharmaceutical industries. In this study, a unique construct was achieved, namely O6, which contains <i>CsCCD2L</i>, <i>UGT74AD1</i>, and <i>UGT709G1</i> genes responsible for the biosynthesis of saffron apocarotenoids driven by a patatFrontiers in nutrition1045979https://www.ebi.ac.uk/biostudies/studies/S-EPMC9748089biostudies-literatureFortification and bioaccessibility of saffron apocarotenoids in potato tubers.PMC9748089Lujan RFrusciante SArgandona JMondejar MLopez-Jimenez AJRubio-Moraga AGomez Gomez LMorote LAhrazem ORambla JLGranell APresa SMartin-Belmonte ANiza EDiretto GfalseFortification and bioaccessibility of saffron apocarotenoids in potato tubers.Carotenoids are C40 isoprenoids with well-established roles in photosynthesis, pollination, photoprotection, and hormone biosynthesis. The enzymatic or ROS-induced cleavage of carotenoids generates a group of compounds named apocarotenoids, with an increasing interest by virtue of their metabolic, physiological, and ecological activities. Both classes are used industrially in a variety of fields as colorants, supplements, and bio-actives. Crocins and picrocrocin, two saffron apocarotenoids, are examples of high-value pigments utilized in the food, feed, and pharmaceutical industries. In this study, a unique construct was achieved, namely O6, which contains <i>CsCCD2L</i>, <i>UGT74AD1</i>, and <i>UGT709G1</i> genes responsible for the biosynthesis of saffron apocarotenoids driven by a patat2022-01-01T00:00:00Z20222025-04-04T08:03:36.207Z2025-04-04T08:03:36.207ZS-EPMC97480893653252510.3389/fnut.2022.1045979