{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Pierce RW"],"funding":["NHLBI NIH HHS"],"pagination":["S97-S102"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9754809"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["149(1 Suppl 1)"],"pubmed_abstract":["<h4>Objectives</h4>To review, analyze, and synthesize the literature on endothelial dysfunction in critically ill children with multiple organ dysfunction syndrome and to develop a consensus biomarker-based definition and diagnostic criteria.<h4>Data sources</h4>Electronic searches of PubMed and Embase were conducted from January 1992 to January 2020, using a combination of medical subject heading terms and key words to define concepts of endothelial dysfunction, pediatric critical illness, and outcomes.<h4>Study selection</h4>Studies were included if they evaluated critically ill children with endothelial dysfunction, evaluated performance characteristics of assessment/scoring tools to screen for endothelial dysfunction, and assessed outcomes related to mortality, functional status, organ"],"journal":["Pediatrics"],"pubmed_title":["Endothelial Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference."],"pmcid":["PMC9754809"],"funding_grant_id":["L30 HL149099"],"pubmed_authors":["Leteurtre S","Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative","Jeffries H","Doctor A","Ouellette Y","Robinson KA","Gorga SM","Typpo KV","Pathan N","Tissieres P","Bembea MM","Muszynski JA","Willson D","Cholette J","Wynn JL","Wainwright MS","Akcan-Arikan A","Lee JH","Parker R","Hall M","Tucci M","Hassinger AB","Irving SY","Farris RWD","Yehya N","Jouvet P","Watson RS","Smith LS","Cheifetz IM","Sanchez-Pinto LN","Faustino EVS","Fitzgerald JC","Prince JM","Carcillo JA","Whitney JE","Leclerc F","Giuliano JS","Pierce RW","Thiagarajan R","Lacroix J","Selewski DT","Pineda J","Alexander P","Brown AM","Odetola F","Rowan CM","Hanson SJ","Thomas N","McKiernan PJ","Eckerle M","Cornell T","Menon K","Weiss S","Agus M","Srinivasan V","Gaies M","Schekerdemian LS","Basu R","Bennett TD","Squires RH","Guilliams K","Lobner K","Laussen P","Ryerson LM","Squires JE","Ward SL","Brandao LR","Sutherland SM","Erickson S","Spaeder MC","Khemani RG","Steiner ME","Checchia P","Fuhrman DY","Monagle P","Tasker RC","Zimmerman JJ","Kannan S","Traube C","Schlapbach LJ","Karam O","Bohn D","Hartman M","Kissoon N","Simon D"],"additional_accession":[]},"is_claimable":false,"name":"Endothelial Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.","description":"<h4>Objectives</h4>To review, analyze, and synthesize the literature on endothelial dysfunction in critically ill children with multiple organ dysfunction syndrome and to develop a consensus biomarker-based definition and diagnostic criteria.<h4>Data sources</h4>Electronic searches of PubMed and Embase were conducted from January 1992 to January 2020, using a combination of medical subject heading terms and key words to define concepts of endothelial dysfunction, pediatric critical illness, and outcomes.<h4>Study selection</h4>Studies were included if they evaluated critically ill children with endothelial dysfunction, evaluated performance characteristics of assessment/scoring tools to screen for endothelial dysfunction, and assessed outcomes related to mortality, functional status, organ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Jan","modification":"2025-05-29T16:30:16.188Z","creation":"2025-05-29T16:30:16.188Z"},"accession":"S-EPMC9754809","cross_references":{"pubmed":["34970676"],"doi":["10.1542/peds.2021-052888O","10.1542/peds.2021-052888o"]}}