{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Yan S"],"funding":["Beijing Hospitals Authority Ascent Plan","National Natural Science Foundation of China","Beijing Municipal Administration of Hospitals Incubating Program","Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support","Beijing Natural Science Foundation"],"pagination":["380-390"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9755097"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["33(1)"],"pubmed_abstract":["<h4>Objective</h4>To investigate the performance of quantitative CT analysis in predicting the prognosis of patients with locally advanced oesophageal squamous cell carcinoma (ESCC) after two cycles of induction chemotherapy before definitive chemoradiotherapy/radiotherapy.<h4>Methods</h4>A total of 110 patients with locally advanced ESCC were retrospectively analysed. Baseline chest CT and CT after two cycles of induction chemotherapy were analysed. A multivariate Cox proportional-hazard regression model was used to identify independent prognostic markers for survival analysis. Then, a CT scoring system was established. Time-dependent receiver operating characteristic (ROC) curve analysis and the Kaplan-Meier method were employed for analysing the prognostic value of the CT scoring system"],"journal":["European radiology"],"pubmed_title":["Quantitative CT evaluation after two cycles of induction chemotherapy to predict prognosis of patients with locally advanced oesophageal squamous cell carcinoma before undergoing definitive chemoradiotherapy/radiotherapy."],"pmcid":["PMC9755097"],"funding_grant_id":["Grant Nos. 91959116 and 81971584","Grant No. ZYLX201803","Grant No. PX2020046","Grant No. Z200015","Grant No. 20191103"],"pubmed_authors":["Li XT","Wei YY","Shi YJ","Shen L","Lu ZH","Zhao B","Yan S","Liu C","Sun YS"],"additional_accession":[]},"is_claimable":false,"name":"Quantitative CT evaluation after two cycles of induction chemotherapy to predict prognosis of patients with locally advanced oesophageal squamous cell carcinoma before undergoing definitive chemoradiotherapy/radiotherapy.","description":"<h4>Objective</h4>To investigate the performance of quantitative CT analysis in predicting the prognosis of patients with locally advanced oesophageal squamous cell carcinoma (ESCC) after two cycles of induction chemotherapy before definitive chemoradiotherapy/radiotherapy.<h4>Methods</h4>A total of 110 patients with locally advanced ESCC were retrospectively analysed. Baseline chest CT and CT after two cycles of induction chemotherapy were analysed. A multivariate Cox proportional-hazard regression model was used to identify independent prognostic markers for survival analysis. Then, a CT scoring system was established. Time-dependent receiver operating characteristic (ROC) curve analysis and the Kaplan-Meier method were employed for analysing the prognostic value of the CT scoring system","dates":{"release":"2023-01-01T00:00:00Z","publication":"2023 Jan","modification":"2025-04-19T18:52:24.848Z","creation":"2025-04-19T18:52:24.848Z"},"accession":"S-EPMC9755097","cross_references":{"pubmed":["35927466"],"doi":["10.1007/s00330-022-08994-y"]}}