biostudies-literatureYan SBeijing Hospitals Authority Ascent PlanNational Natural Science Foundation of ChinaBeijing Municipal Administration of Hospitals Incubating ProgramBeijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding SupportBeijing Natural Science Foundation380-390https://www.ebi.ac.uk/biostudies/studies/S-EPMC9755097biostudies-literatureUnknown33(1)<h4>Objective</h4>To investigate the performance of quantitative CT analysis in predicting the prognosis of patients with locally advanced oesophageal squamous cell carcinoma (ESCC) after two cycles of induction chemotherapy before definitive chemoradiotherapy/radiotherapy.<h4>Methods</h4>A total of 110 patients with locally advanced ESCC were retrospectively analysed. Baseline chest CT and CT after two cycles of induction chemotherapy were analysed. A multivariate Cox proportional-hazard regression model was used to identify independent prognostic markers for survival analysis. Then, a CT scoring system was established. Time-dependent receiver operating characteristic (ROC) curve analysis and the Kaplan-Meier method were employed for analysing the prognostic value of the CT scoring systemEuropean radiologyQuantitative CT evaluation after two cycles of induction chemotherapy to predict prognosis of patients with locally advanced oesophageal squamous cell carcinoma before undergoing definitive chemoradiotherapy/radiotherapy.PMC9755097Grant Nos. 91959116 and 81971584Grant No. ZYLX201803Grant No. PX2020046Grant No. Z200015Grant No. 20191103Li XTWei YYShi YJShen LLu ZHZhao BYan SLiu CSun YSfalseQuantitative CT evaluation after two cycles of induction chemotherapy to predict prognosis of patients with locally advanced oesophageal squamous cell carcinoma before undergoing definitive chemoradiotherapy/radiotherapy.<h4>Objective</h4>To investigate the performance of quantitative CT analysis in predicting the prognosis of patients with locally advanced oesophageal squamous cell carcinoma (ESCC) after two cycles of induction chemotherapy before definitive chemoradiotherapy/radiotherapy.<h4>Methods</h4>A total of 110 patients with locally advanced ESCC were retrospectively analysed. Baseline chest CT and CT after two cycles of induction chemotherapy were analysed. A multivariate Cox proportional-hazard regression model was used to identify independent prognostic markers for survival analysis. Then, a CT scoring system was established. Time-dependent receiver operating characteristic (ROC) curve analysis and the Kaplan-Meier method were employed for analysing the prognostic value of the CT scoring system2023-01-01T00:00:00Z2023 Jan2025-04-19T18:52:24.848Z2025-04-19T18:52:24.848ZS-EPMC97550973592746610.1007/s00330-022-08994-y