{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["16"],"submitter":["Hussain N"],"pubmed_abstract":["The \"Severe Acute Respiratory Syndrome\" (SARS), which has relation to the coronavirus-2 considered to be a major cause of the disease addressed by COVID-19. COVID-19 requires the angiotensin converting enzyme 2 (ACE-2), which is considered to be the target receptor of the host cells. The intention of this practical research study was to observe ACE I/D polymorphism association with COVID-19 and also the <i>in-silico</i> screening of potential phytochemicals against COVID-19. This study incorporated total of 320 blood samples; of which 160 were collected from COVID-19 patients and 160 were collected from healthy controls. DNA extraction was conducted from whole genomic blood and afterward, the banding patterns of ACE polymorphism were identified by the application of a nested polymerase cha"],"journal":["Bioinformatics and biology insights"],"pagination":["11779322221139061"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9760525"],"repository":["biostudies-literature"],"pubmed_title":["The Biological Causes and Consequences of COVID-19: ACE I/D Polymorphism and In-Silico Screening of Potential Bioactive Phytochemicals Against COVID-19."],"pmcid":["PMC9760525"],"pubmed_authors":["Mumtaz M","Hussain N","Adil M","Waseem M"],"additional_accession":[]},"is_claimable":false,"name":"The Biological Causes and Consequences of COVID-19: ACE I/D Polymorphism and In-Silico Screening of Potential Bioactive Phytochemicals Against COVID-19.","description":"The \"Severe Acute Respiratory Syndrome\" (SARS), which has relation to the coronavirus-2 considered to be a major cause of the disease addressed by COVID-19. COVID-19 requires the angiotensin converting enzyme 2 (ACE-2), which is considered to be the target receptor of the host cells. The intention of this practical research study was to observe ACE I/D polymorphism association with COVID-19 and also the <i>in-silico</i> screening of potential phytochemicals against COVID-19. This study incorporated total of 320 blood samples; of which 160 were collected from COVID-19 patients and 160 were collected from healthy controls. DNA extraction was conducted from whole genomic blood and afterward, the banding patterns of ACE polymorphism were identified by the application of a nested polymerase cha","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2025-04-05T07:25:08.226Z","creation":"2024-11-09T10:37:14.522Z"},"accession":"S-EPMC9760525","cross_references":{"pubmed":["36540330"],"doi":["10.1177/11779322221139061"]}}