{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Diez-Ricote L"],"funding":["CIBER de Fisiopatología de la Obesidad y Nutrición","Amgen","Consejería de Salud y Familias, Junta de Andalucía","FEDER","Generalitat Valenciana","Novo Nordisk","Instituto de Salud Carlos III","European Research Council","Ministerio de Ciencia e Innovación","Instituto Danone","Fundació la Marató de TV3","Catalan Institution for Research and Advanced Studies","Government of Navarra Department of Health","Biotechnology and Biological Sciences Research Council","Sanofi","MSD","European Regional Development Fund"],"pagination":["1565-1579"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9761742"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["116(6)"],"pubmed_abstract":["<h4>Background</h4>Choline and betaine intakes have been related to cardiovascular health.<h4>Objectives</h4>We aimed to explore the relation between 1-y changes in dietary intake of choline or betaine and 1-y changes in cardiometabolic and renal function traits within the frame of the PREDIMED (PREvención con DIeta MEDiterránea)-Plus trial.<h4>Methods</h4>We used baseline and 1-y follow-up data from 5613 participants (48.2% female and 51.8% male; mean ± SD age: 65.01 ± 4.91 y) to assess cardiometabolic traits, and 3367 participants to assess renal function, of the Spanish PREDIMED-Plus trial. Participants met ≥3 criteria of metabolic syndrome and had overweight or obesity [BMI (in kg/m2) ≥27 and ≤40]. These criteria were similar to those of the PREDIMED parent study. Dietary intakes of ch"],"journal":["The American journal of clinical nutrition"],"pubmed_title":["One-year longitudinal association between changes in dietary choline or betaine intake and cardiometabolic variables in the PREvencion con DIeta MEDiterranea-Plus (PREDIMED-Plus) trial."],"pmcid":["PMC9761742"],"funding_grant_id":["#340918","2013ACUP00194","BB/S020845/1","PCI2018-093009","340918","PI0137/2018","61/2015","PI0458/2013","FJC2018-038168-I","PROMETEO/2017/017","PS0358/2016","RTI2018-095569-B-I00","35/2011","201630.10"],"pubmed_authors":["Concejo MJ","Tojal-Sierra L","Mico V","Lopez-Miranda J","Pinto X","Diez-Ricote L","Gaforio JJ","Estruch R","Basterra-Gortari J","Gomez-Bellvert N","Warnberg J","Chaplin A","Herraiz X","Salas-Salvado J","Vidal J","Martin Sanchez V","Vazquez-Ruiz Z","Tur JA","Martinez-Gonzalez MA","Salaverria-Lete I","Bueno-Cavanillas A","Babio N","Vioque J","Malcampo M","Goday A","Martinez-Urbistondo D","Goni Ochandorena E","Serra-Majem L","Tinahones FJ","Martinez JA","Lapetra J","Alonso-Gomez AM","Garcia-Rios A","Murphy M","Mas Fontao S","Ordovas JM","Bernal-Lopez RM","Romaguera D","Garcia Rodriguez A","Sorli JV","Gasulla G","Corella D","Ros E","Garcia-Gavilan JF","San-Cristobal R","Matia-Martin P","Ortega-Azorin C","Santos-Lozano JM","Daimiel L"],"additional_accession":[]},"is_claimable":false,"name":"One-year longitudinal association between changes in dietary choline or betaine intake and cardiometabolic variables in the PREvencion con DIeta MEDiterranea-Plus (PREDIMED-Plus) trial.","description":"<h4>Background</h4>Choline and betaine intakes have been related to cardiovascular health.<h4>Objectives</h4>We aimed to explore the relation between 1-y changes in dietary intake of choline or betaine and 1-y changes in cardiometabolic and renal function traits within the frame of the PREDIMED (PREvención con DIeta MEDiterránea)-Plus trial.<h4>Methods</h4>We used baseline and 1-y follow-up data from 5613 participants (48.2% female and 51.8% male; mean ± SD age: 65.01 ± 4.91 y) to assess cardiometabolic traits, and 3367 participants to assess renal function, of the Spanish PREDIMED-Plus trial. Participants met ≥3 criteria of metabolic syndrome and had overweight or obesity [BMI (in kg/m2) ≥27 and ≤40]. These criteria were similar to those of the PREDIMED parent study. Dietary intakes of ch","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-04T19:49:25.777Z","creation":"2025-04-04T19:49:25.777Z"},"accession":"S-EPMC9761742","cross_references":{"pubmed":["36124652"],"doi":["10.1093/ajcn/nqac255"]}}