{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["22(1)"],"submitter":["Graneli C"],"funding":["Lund University"],"pubmed_abstract":["<h4>Background</h4>In the validation of new imaging technology for children with Hirschsprung's disease (HSCR), basic anatomical parameters of the bowel wall must be established specifically for this patient group.<h4>Aim</h4>To explore differences in histoanatomical layers of bowel wall, comparing ganglionic and aganglionic bowel walls, and to examine if the bowel wall thickness is linked to patient weight.<h4>Methods</h4>This was an observational study of bowel specimens from children weighing 0-10 kg, operated on consecutively during 2018-2020. Ganglionic and aganglionic bowel walls were measured in digitalized microscopy images from 10 sites per trans-sectional specimen and compared regarding the thickness of their histoanatomical layers.<h4>Results</h4>Bowel walls were measured in 21 "],"journal":["BMC pediatrics"],"pagination":["723"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9764572"],"repository":["biostudies-literature"],"pubmed_title":["Histopathological dimensions differ between aganglionic and ganglionic bowel wall in children with Hirschsprung's disease."],"pmcid":["PMC9764572"],"pubmed_authors":["Gottberg E","Cinthio M","Mitev RM","Stenstrom P","Hagelsteen K","Erlov T","Gisselsson D","Jansson T","Graneli C","Patarroyo S"],"additional_accession":[]},"is_claimable":false,"name":"Histopathological dimensions differ between aganglionic and ganglionic bowel wall in children with Hirschsprung's disease.","description":"<h4>Background</h4>In the validation of new imaging technology for children with Hirschsprung's disease (HSCR), basic anatomical parameters of the bowel wall must be established specifically for this patient group.<h4>Aim</h4>To explore differences in histoanatomical layers of bowel wall, comparing ganglionic and aganglionic bowel walls, and to examine if the bowel wall thickness is linked to patient weight.<h4>Methods</h4>This was an observational study of bowel specimens from children weighing 0-10 kg, operated on consecutively during 2018-2020. Ganglionic and aganglionic bowel walls were measured in digitalized microscopy images from 10 sites per trans-sectional specimen and compared regarding the thickness of their histoanatomical layers.<h4>Results</h4>Bowel walls were measured in 21 ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-04T22:36:30.744Z","creation":"2024-11-19T15:24:28.901Z"},"accession":"S-EPMC9764572","cross_references":{"pubmed":["36536313"],"doi":["10.1186/s12887-022-03792-3"]}}