{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Aerts R"],"pubmed_abstract":["<h4>Introduction</h4>Serum Mucorales PCR can precede the final diagnosis of invasive mucormycosis by several days or weeks and could therefore be useful as a non-invasive screening tool.<h4>Methods</h4>We assessed the performance of a commercial Mucorales PCR assay (MucorGenius®, PathoNostics, Maastricht, The Netherlands) on prospectively collected banked sera from hematology patients at risk for invasive mould infections. We evaluated if there is an underestimated incidence of missed Mucorales co-infections in patients with invasive aspergillosis (IA). We tested Mucorales PCR on the sera of all patients with a diagnosis of at least possible IA (EORTC-MSGERC consensus criteria) before the start of any antifungal therapy, and in a control group of similar high-risk hematology patients witho"],"journal":["Frontiers in cellular and infection microbiology"],"pagination":["1080921"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9774025"],"repository":["biostudies-literature"],"pubmed_title":["Blood Mucorales PCR to track down <i>Aspergillus</i> and Mucorales co-infections in at-risk hematology patients: A case-control study."],"pmcid":["PMC9774025"],"pubmed_authors":["Schauwvlieghe A","Lagrou K","Aerts R","Bevers S","Beuselinck K","Maertens J"],"additional_accession":[]},"is_claimable":false,"name":"Blood Mucorales PCR to track down <i>Aspergillus</i> and Mucorales co-infections in at-risk hematology patients: A case-control study.","description":"<h4>Introduction</h4>Serum Mucorales PCR can precede the final diagnosis of invasive mucormycosis by several days or weeks and could therefore be useful as a non-invasive screening tool.<h4>Methods</h4>We assessed the performance of a commercial Mucorales PCR assay (MucorGenius®, PathoNostics, Maastricht, The Netherlands) on prospectively collected banked sera from hematology patients at risk for invasive mould infections. We evaluated if there is an underestimated incidence of missed Mucorales co-infections in patients with invasive aspergillosis (IA). We tested Mucorales PCR on the sera of all patients with a diagnosis of at least possible IA (EORTC-MSGERC consensus criteria) before the start of any antifungal therapy, and in a control group of similar high-risk hematology patients witho","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022","modification":"2026-07-14T17:37:09.799Z","creation":"2025-04-05T21:04:52.705Z"},"accession":"S-EPMC9774025","cross_references":{"pubmed":["36569194"],"doi":["10.3389/fcimb.2022.1080921"]}}