{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Jiao D"],"funding":["Construction of Rural Revitalization Industry Technology Innovation Center and Demonstration Base in Yellow River Delta","Study on the Haplotype Genetic Expression of ADRB3- Energy Metabolism Gene Group in the Xinjiang Sheep Breeding Population","Strategic Priority Research Program (A) of Chinese Academy of Sciences","the Special Funds for Scientific and Technological Innovation and Development in Gansu Province","Hundred Talents Program of Chinese Academy of Sciences","the Special Funds for Scientific and Technological Innovation and Development in Gansu Province (Research and Development Center of Desert Nutrition and Medicinal Plant Germplasm Innovation)"],"pagination":["3486"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC9774518"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["12(24)"],"pubmed_abstract":["Agriophyllum squarrosum (sand rice), a widespread desert plant, possesses anti-hyperglycemic and anti-inflammatory properties, and has been used in traditional Chinese medicine for many years. However, its effects on ruminants are unknown. To fill this gap, we examined the effects of A. squarrosum on the immune and anti-inflammatory responses of lambs. A total of 23, 6-month-old Tan ewe-lambs (27.6 ± 0.47 kg) were divided into four groups and offered a basic diet (C—control), or a diet that contained 10%, 20%, or 30% A. squarrosum, on a dry matter basis, for 128 days. Serum concentrations of total cholesterol were lower (p = 0.004) in the 30% supplemented lambs than controls, while concentrations of high-density lipoprotein cholesterol were lower (p = 0.006) in the 10% and 20%, but not in "],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Supplementing Diets with <i>Agriophyllum squarrosum</i> Reduced Blood Lipids, Enhanced Immunity and Anti-Inflammatory Capacities, and Mediated Lipid Metabolism in Tan Lambs."],"pmcid":["PMC9774518"],"funding_grant_id":["Y939BD1002","XDA26040301","Y62972101","E141050101","2019CA009"],"pubmed_authors":["Yang G","Liang Y","Zhou S","Hickford J","Ma X","Cong H","Jiao D","Degen AA","Zhou H","Shi X","Wu X"],"additional_accession":[]},"is_claimable":false,"name":"Supplementing Diets with <i>Agriophyllum squarrosum</i> Reduced Blood Lipids, Enhanced Immunity and Anti-Inflammatory Capacities, and Mediated Lipid Metabolism in Tan Lambs.","description":"Agriophyllum squarrosum (sand rice), a widespread desert plant, possesses anti-hyperglycemic and anti-inflammatory properties, and has been used in traditional Chinese medicine for many years. However, its effects on ruminants are unknown. To fill this gap, we examined the effects of A. squarrosum on the immune and anti-inflammatory responses of lambs. A total of 23, 6-month-old Tan ewe-lambs (27.6 ± 0.47 kg) were divided into four groups and offered a basic diet (C—control), or a diet that contained 10%, 20%, or 30% A. squarrosum, on a dry matter basis, for 128 days. Serum concentrations of total cholesterol were lower (p = 0.004) in the 30% supplemented lambs than controls, while concentrations of high-density lipoprotein cholesterol were lower (p = 0.006) in the 10% and 20%, but not in ","dates":{"release":"2022-01-01T00:00:00Z","publication":"2022 Dec","modification":"2025-04-18T16:33:48.883Z","creation":"2025-04-07T03:49:04.183Z"},"accession":"S-EPMC9774518","cross_references":{"pubmed":["36552407"],"doi":["10.3390/ani12243486"]}}